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Ligand-Specific Restriction of Extracellular Conformational Dynamics Constrains Signaling of the M2 Muscarinic Receptor.
Bermudez, Marcel; Bock, Andreas; Krebs, Fabian; Holzgrabe, Ulrike; Mohr, Klaus; Lohse, Martin J; Wolber, Gerhard.
Afiliação
  • Bermudez M; Institute of Pharmacy, Freie Universität Berlin , Königin-Luise-Straße 2 und 4, 14195 Berlin, Germany.
  • Bock A; Institute of Pharmacology and Toxicology, University of Würzburg , Versbacher Strasse 9, 97078 Würzburg, Germany.
  • Krebs F; Max Delbrück Center for Molecular Medicine , Robert-Rössle-Str. 10, 13125 Berlin, Germany.
  • Holzgrabe U; Pharmacology and Toxicology Section, Institute of Pharmacy, University of Bonn , Gerhard-Domagk-Straße 3, 53121 Bonn, Germany.
  • Mohr K; Institute of Pharmacy, University of Würzburg , Am Hubland, 97074 Würzburg, Germany.
  • Lohse MJ; Pharmacology and Toxicology Section, Institute of Pharmacy, University of Bonn , Gerhard-Domagk-Straße 3, 53121 Bonn, Germany.
  • Wolber G; Institute of Pharmacology and Toxicology, University of Würzburg , Versbacher Strasse 9, 97078 Würzburg, Germany.
ACS Chem Biol ; 12(7): 1743-1748, 2017 07 21.
Article em En | MEDLINE | ID: mdl-28585805
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Transdução de Sinais / Receptor Muscarínico M2 / Simulação de Dinâmica Molecular Idioma: En Ano de publicação: 2017 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Transdução de Sinais / Receptor Muscarínico M2 / Simulação de Dinâmica Molecular Idioma: En Ano de publicação: 2017 Tipo de documento: Article