Submicroscopic malaria infections in pregnant women from six departments in Haiti.
Trop Med Int Health
; 22(8): 1030-1036, 2017 08.
Article
em En
| MEDLINE
| ID: mdl-28609010
ABSTRACT
OBJECTIVES:
To describe the epidemiology of malaria in pregnancy in Haiti.METHODS:
Cross-sectional study among pregnant women in six departments of Haiti. After obtaining informed consent, whole blood samples and demographic surveys were collected to investigate malaria prevalence, anaemia and socio-behavioural risk factors for infection, respectively. A total of 311 pregnant women were screened for Plasmodium falciparum infection using a rapid diagnostic test (RDT), microscopy and a novel, quantitative reverse transcriptase polymerase chain reaction method (qRT-PCR).RESULTS:
Overall, 1.2% (4/311) of pregnant women were tested positive for malaria infection by both microscopy and RDT. However, using the qRT-PCR, 16.4% (51/311) of pregnant women were positive. The prevalence of malaria infection varied with geographical locations ranging between 0% and 46.4%. Additionally, 53% of pregnant women had some form of anaemia; however, no significant association was found between anaemia and submicroscopic malaria infection. The socio-behavioural risk factors identified to be protective of malaria infection were marital status (P < 0.05) and travel within one month prior to screening (P < 0.05).CONCLUSION:
This study is the first to document the high prevalence of submicroscopic malaria infections among pregnant women in Haiti and identify social and behavioural risk factors for disease transmission.Palavras-chave
Texto completo:
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Base de dados:
MEDLINE
Assunto principal:
Plasmodium falciparum
/
Complicações Infecciosas na Gravidez
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Malária Falciparum
Idioma:
En
Ano de publicação:
2017
Tipo de documento:
Article