Epithelial-mesenchymal transition and cancer stem cell-like phenotype induced by Twist1 contribute to acquired resistance to irinotecan in colon cancer.

Yang, Yong; Wang, Guoxin; Zhu, Dajian; Huang, Yanfeng; Luo, Yong; Su, Pengfei; Chen, Xiaowu; Wang, Qian

Yang, Yong; Wang, Guoxin; Zhu, Dajian; Huang, Yanfeng; Luo, Yong; Su, Pengfei; Chen, Xiaowu; Wang, Qian.

Afiliação

Yang Y; Department of Gastrointestinal Surgery, Shunde First People's Hospital Affiliated to Southern Medical University, Shunde, Guangdong 528300, P.R. China.
Wang G; Department of Gastrointestinal Surgery, Shunde First People's Hospital Affiliated to Southern Medical University, Shunde, Guangdong 528300, P.R. China.
Zhu D; Department of Gastrointestinal Surgery, Shunde Women and Children's Hospital Affiliated to Jinan University, Shunde, Guangdong 528300, P.R. China.
Huang Y; Department of Traditional Chinese Medicine, Shunde First People's Hospital Affiliated to Southern Medical University, Shunde, Guangdong 528300, P.R. China.
Luo Y; Department of Gastrointestinal Surgery, Shunde First People's Hospital Affiliated to Southern Medical University, Shunde, Guangdong 528300, P.R. China.
Su P; Department of Gastrointestinal Surgery, Shunde First People's Hospital Affiliated to Southern Medical University, Shunde, Guangdong 528300, P.R. China.
Chen X; Department of Gastrointestinal Surgery, Shunde First People's Hospital Affiliated to Southern Medical University, Shunde, Guangdong 528300, P.R. China.
Wang Q; Department of Hepatobiliary Surgery, the First Affiliated Hospital of Sun Yat-Sen University, Guangzhou, Guangdong 510080, P.R. China.

Int J Oncol ; 51(2): 515-524, 2017 Aug.

Article em En | MEDLINE | ID: mdl-28627611

Assuntos

Camptotecina/análogos & derivados; Proliferação de Células/genética; Neoplasias do Colo/tratamento farmacológico; Proteínas Nucleares/genética; Proteína 1 Relacionada a Twist/genética; Camptotecina/administração & dosagem; Camptotecina/efeitos adversos; Movimento Celular/genética; Neoplasias do Colo/genética; Neoplasias do Colo/patologia; Resistencia a Medicamentos Antineoplásicos/genética; Transição Epitelial-Mesenquimal/genética; Regulação Neoplásica da Expressão Gênica/efeitos dos fármacos; Humanos; Irinotecano; Invasividade Neoplásica/genética; Invasividade Neoplásica/patologia; Células-Tronco Neoplásicas/efeitos dos fármacos; Proteínas Nucleares/antagonistas & inibidores; RNA Interferente Pequeno/genética; Transfecção; Proteína 1 Relacionada a Twist/antagonistas & inibidores

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Camptotecina / Proteínas Nucleares / Neoplasias do Colo / Proliferação de Células / Proteína 1 Relacionada a Twist Idioma: En Ano de publicação: 2017 Tipo de documento: Article

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