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Benzoxaborole Antimalarial Agents. Part 5. Lead Optimization of Novel Amide Pyrazinyloxy Benzoxaboroles and Identification of a Preclinical Candidate.
Zhang, Yong-Kang; Plattner, Jacob J; Easom, Eric E; Jacobs, Robert T; Guo, Denghui; Freund, Yvonne R; Berry, Pamela; Ciaravino, Vic; Erve, John C L; Rosenthal, Philip J; Campo, Brice; Gamo, Francisco-Javier; Sanz, Laura M; Cao, Jianxin.
Afiliação
  • Zhang YK; Anacor Pharmaceuticals, Inc. , 1020 E. Meadow Circle, Palo Alto, California 94303, United States.
  • Plattner JJ; Anacor Pharmaceuticals, Inc. , 1020 E. Meadow Circle, Palo Alto, California 94303, United States.
  • Easom EE; Anacor Pharmaceuticals, Inc. , 1020 E. Meadow Circle, Palo Alto, California 94303, United States.
  • Jacobs RT; Anacor Pharmaceuticals, Inc. , 1020 E. Meadow Circle, Palo Alto, California 94303, United States.
  • Guo D; Department of Medicine, University of California, San Francisco , Box 0811, San Francisco, California 94143, United States.
  • Freund YR; Anacor Pharmaceuticals, Inc. , 1020 E. Meadow Circle, Palo Alto, California 94303, United States.
  • Berry P; Anacor Pharmaceuticals, Inc. , 1020 E. Meadow Circle, Palo Alto, California 94303, United States.
  • Ciaravino V; Anacor Pharmaceuticals, Inc. , 1020 E. Meadow Circle, Palo Alto, California 94303, United States.
  • Erve JCL; Anacor Pharmaceuticals, Inc. , 1020 E. Meadow Circle, Palo Alto, California 94303, United States.
  • Rosenthal PJ; Department of Medicine, University of California, San Francisco , Box 0811, San Francisco, California 94143, United States.
  • Campo B; Medicines for Malaria Venture, International Center Cointrin , Block G, 20 Route de Pré-Bois, POB 1826, CH - 1215 Geneva, Switzerland.
  • Gamo FJ; Diseases of the Developing World, GlaxoSmithKline , Severo Ochoa 2, 28760, Tres Cantos, Spain.
  • Sanz LM; Diseases of the Developing World, GlaxoSmithKline , Severo Ochoa 2, 28760, Tres Cantos, Spain.
  • Cao J; Shanghai ChemPartner , 998 Ha-lei Road, Zhangjiang High-tech Park, Pudong New Area, Shanghai 201203, China.
J Med Chem ; 60(13): 5889-5908, 2017 07 13.
Article em En | MEDLINE | ID: mdl-28635296
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Plasmodium berghei / Plasmodium falciparum / Compostos de Boro / Malária / Antimaláricos Idioma: En Ano de publicação: 2017 Tipo de documento: Article
Texto completo
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XML
PubMed Links
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Plasmodium berghei / Plasmodium falciparum / Compostos de Boro / Malária / Antimaláricos Idioma: En Ano de publicação: 2017 Tipo de documento: Article