NPM1 for MRD? Droplet Like It's Hot!

Wertheim, Gerald B W; Bagg, Adam

Wertheim, Gerald B W; Bagg, Adam.

Afiliação

Wertheim GBW; Division of Hematopathology, Department of Pathology and Laboratory Medicine, University of Pennsylvania, Philadelphia, Pennsylvania.
Bagg A; Division of Hematopathology, Department of Pathology and Laboratory Medicine, University of Pennsylvania, Philadelphia, Pennsylvania. Electronic address: adambagg@mail.med.upenn.edu.

J Mol Diagn ; 19(4): 498-501, 2017 07.

Article em En | MEDLINE | ID: mdl-28645444

RESUMO

This commentary highlights the article by Mencia-Trinchant et al that describes a novel digital PCR assay for sensitive detection of minimal residual disease in NPM1 mutated acute myeloid leukemia.

Assuntos

Leucemia Mieloide Aguda/genética; Mutação; Neoplasia Residual/genética; Proteínas Nucleares/genética; Análise Mutacional de DNA/métodos; Humanos; Leucemia Mieloide Aguda/diagnóstico; Neoplasia Residual/diagnóstico; Nucleofosmina; Reação em Cadeia da Polimerase/métodos

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Proteínas Nucleares / Leucemia Mieloide Aguda / Neoplasia Residual / Mutação Idioma: En Ano de publicação: 2017 Tipo de documento: Article

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