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Genetic and epigenetic inactivation of SESTRIN1 controls mTORC1 and response to EZH2 inhibition in follicular lymphoma.
Oricchio, Elisa; Katanayeva, Natalya; Donaldson, Maria Christine; Sungalee, Stephanie; Pasion, Joyce P; Béguelin, Wendy; Battistello, Elena; Sanghvi, Viraj R; Jiang, Man; Jiang, Yanwen; Teater, Matt; Parmigiani, Anita; Budanov, Andrei V; Chan, Fong Chun; Shah, Sohrab P; Kridel, Robert; Melnick, Ari M; Ciriello, Giovanni; Wendel, Hans-Guido.
Afiliação
  • Oricchio E; Swiss Institute for Experimental Cancer Research (ISREC), School of Life Sciences, École Polytechnique Fédérale de Lausanne (EPFL), 1015 Lausanne, Switzerland. elisa.oricchio@epfl.ch.
  • Katanayeva N; Swiss Institute for Experimental Cancer Research (ISREC), School of Life Sciences, École Polytechnique Fédérale de Lausanne (EPFL), 1015 Lausanne, Switzerland.
  • Donaldson MC; Swiss Institute for Experimental Cancer Research (ISREC), School of Life Sciences, École Polytechnique Fédérale de Lausanne (EPFL), 1015 Lausanne, Switzerland.
  • Sungalee S; Swiss Institute for Experimental Cancer Research (ISREC), School of Life Sciences, École Polytechnique Fédérale de Lausanne (EPFL), 1015 Lausanne, Switzerland.
  • Pasion JP; Cancer Biology and Genetics Program, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
  • Béguelin W; Division of Hematology/Oncology, Weill Cornell Medical College, Cornell University, 1300 York Avenue, New York, NY 10065, USA.
  • Battistello E; Swiss Institute for Experimental Cancer Research (ISREC), School of Life Sciences, École Polytechnique Fédérale de Lausanne (EPFL), 1015 Lausanne, Switzerland.
  • Sanghvi VR; Department of Computational Biology, University of Lausanne, 1005 Lausanne, Switzerland.
  • Jiang M; Cancer Biology and Genetics Program, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
  • Jiang Y; Cancer Biology and Genetics Program, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
  • Teater M; Institute for Computational Biomedicine, Weill Cornell Medical College, Cornell University, New York, NY 10065, USA.
  • Parmigiani A; Institute for Computational Biomedicine, Weill Cornell Medical College, Cornell University, New York, NY 10065, USA.
  • Budanov AV; Department of Human and Molecular Genetics, Goodwin Research Laboratories, Massey Cancer Center, Virginia Commonwealth University, Richmond, VA 23298, USA.
  • Chan FC; Department of Human and Molecular Genetics, Goodwin Research Laboratories, Massey Cancer Center, Virginia Commonwealth University, Richmond, VA 23298, USA.
  • Shah SP; School of Biochemistry and Immunology, Trinity Biomedical Sciences Institute, Trinity College Dublin, Pearse Street, Dublin 2, Ireland.
  • Kridel R; Centre for Lymphoid Cancer, BC Cancer Agency, Vancouver, British Columbia V5Z 1L3, Canada.
  • Melnick AM; Bioinformatics Graduate Program, University of British Columbia, Vancouver, British Columbia, Canada.
  • Ciriello G; Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, British Columbia, Canada.
  • Wendel HG; Department of Molecular Oncology, BC Cancer Agency, Vancouver, British Columbia, Canada.
Sci Transl Med ; 9(396)2017 06 28.
Article em En | MEDLINE | ID: mdl-28659443
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Linfoma Folicular / Epigênese Genética / Proteína Potenciadora do Homólogo 2 de Zeste / Alvo Mecanístico do Complexo 1 de Rapamicina / Proteínas de Choque Térmico Idioma: En Ano de publicação: 2017 Tipo de documento: Article
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Linfoma Folicular / Epigênese Genética / Proteína Potenciadora do Homólogo 2 de Zeste / Alvo Mecanístico do Complexo 1 de Rapamicina / Proteínas de Choque Térmico Idioma: En Ano de publicação: 2017 Tipo de documento: Article