Arterial blood pressure responses to short-term exposure to fine and ultrafine particles from indoor sources - A randomized sham-controlled exposure study of healthy volunteers.
Environ Res
; 158: 225-232, 2017 10.
Article
em En
| MEDLINE
| ID: mdl-28662448
ABSTRACT
OBJECTIVES:
Particulate air pollution is linked to adverse cardiovascular effects. The aim of the study was to investigate the effect of short-term exposure to indoor particles on blood pressure (BP).METHODS:
We analyzed the association of particle emissions from indoor sources (candle burning, toasting bread, frying sausages) with BP changes in 54 healthy volunteers in a randomized cross-over controlled exposure study. Particle mass concentration (PMC), size-specific particle number concentration (PNC) and lung-deposited particle surface area concentration (PSC) were measured during the 2h exposure. Systolic and diastolic blood pressure were measured before, during, directly, 2, 4 and 24h after exposure. We performed multiple mixed linear regression analyses of different particle metrics and BP.RESULTS:
BP significantly increased with increasing PMC, PSC and PNC resulting from toasting bread. For example, an increase per 10µg/m3 PM10 and PM2.5, systolic BP increased at all time points with largest changes 1h after exposure initiation of 1.5mmHg (95%-CI 1.1; 1.9) and of 2.2mmHg (95%-CI 1.3; 3.1), respectively.CONCLUSIONS:
Our study suggests an association of short-term exposure to fine and ultrafine particles emitted from toasting bread with increases in BP. Particles emitted from frying sausages and candle burning did not consistently affect BP.Palavras-chave
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Base de dados:
MEDLINE
Assunto principal:
Pressão Sanguínea
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Poluição do Ar em Ambientes Fechados
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Poluentes Atmosféricos
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Exposição Ambiental
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Material Particulado
Idioma:
En
Ano de publicação:
2017
Tipo de documento:
Article