Thrombin-induced, TNFR-dependent miR-181c downregulation promotes MLL1 and NF-&#954;B target gene expression in human microglia.

Yin, Min; Chen, Zhiying; Ouyang, Yetong; Zhang, Huiyan; Wan, Zhigang; Wang, Han; Wu, Wei; Yin, Xiaoping

Thrombin-induced, TNFR-dependent miR-181c downregulation promotes MLL1 and NF-κB target gene expression in human microglia.

Yin, Min; Chen, Zhiying; Ouyang, Yetong; Zhang, Huiyan; Wan, Zhigang; Wang, Han; Wu, Wei; Yin, Xiaoping.

Afiliação

Yin M; Department of Neurology, The Second Affiliated Hospital of Nanchang University, No. 1 Minde Road, Nanchang, 330006, Jiangxi Province, China.
Chen Z; Department of Neurology, The Affiliated Hospital of Jiujiang University, Jiujiang, 332000, Jiangxi Province, China.
Ouyang Y; Department of Neurology, The Second Affiliated Hospital of Nanchang University, No. 1 Minde Road, Nanchang, 330006, Jiangxi Province, China.
Zhang H; Department of Neurology, The Second Affiliated Hospital of Nanchang University, No. 1 Minde Road, Nanchang, 330006, Jiangxi Province, China.
Wan Z; Department of Neurology, The Second Affiliated Hospital of Nanchang University, No. 1 Minde Road, Nanchang, 330006, Jiangxi Province, China.
Wang H; Department of Neurology, The Second Affiliated Hospital of Nanchang University, No. 1 Minde Road, Nanchang, 330006, Jiangxi Province, China.
Wu W; Department of Neurology, The Second Affiliated Hospital of Nanchang University, No. 1 Minde Road, Nanchang, 330006, Jiangxi Province, China. 13807038803@163.com.
Yin X; Department of Neurology, The Second Affiliated Hospital of Nanchang University, No. 1 Minde Road, Nanchang, 330006, Jiangxi Province, China. xpy19700216@163.com.

J Neuroinflammation ; 14(1): 132, 2017 06 29.

Article em En | MEDLINE | ID: mdl-28662718

Assuntos

Histona-Lisina N-Metiltransferase/biossíntese; MicroRNAs/metabolismo; Microglia/metabolismo; Proteína de Leucina Linfoide-Mieloide/biossíntese; NF-kappa B/biossíntese; Receptores do Fator de Necrose Tumoral/metabolismo; Trombina/farmacologia; Adulto; Células Cultivadas; Regulação para Baixo/efeitos dos fármacos; Regulação para Baixo/fisiologia; Feminino; Expressão Gênica; Células HEK293; Histona-Lisina N-Metiltransferase/genética; Humanos; Masculino; Microglia/efeitos dos fármacos; Pessoa de Meia-Idade; Proteína de Leucina Linfoide-Mieloide/genética; NF-kappa B/genética

Palavras-chave

ICH; Intracerebral hemorrhage; MicroRNA; Microglia; Thrombin

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Trombina / NF-kappa B / Histona-Lisina N-Metiltransferase / Receptores do Fator de Necrose Tumoral / Microglia / MicroRNAs / Proteína de Leucina Linfoide-Mieloide Idioma: En Ano de publicação: 2017 Tipo de documento: Article

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