Electrotaxis of cardiac progenitor cells, cardiac fibroblasts, and induced pluripotent stem cell-derived cardiac progenitor cells requires serum and is directed via PI3'K pathways.

Frederich, Bert J; Timofeyev, Valeriy; Thai, Phung N; Haddad, Michael J; Poe, Adam J; Lau, Victor C; Moshref, Maryam; Knowlton, Anne A; Sirish, Padmini; Chiamvimonvat, Nipavan

Frederich, Bert J; Timofeyev, Valeriy; Thai, Phung N; Haddad, Michael J; Poe, Adam J; Lau, Victor C; Moshref, Maryam; Knowlton, Anne A; Sirish, Padmini; Chiamvimonvat, Nipavan.

Afiliação

Frederich BJ; Division of Cardiovascular Medicine, University of California, Davis, California.
Timofeyev V; Division of Cardiovascular Medicine, University of California, Davis, California.
Thai PN; Division of Cardiovascular Medicine, University of California, Davis, California.
Haddad MJ; Division of Cardiovascular Medicine, University of California, Davis, California.
Poe AJ; Division of Cardiovascular Medicine, University of California, Davis, California.
Lau VC; Division of Cardiovascular Medicine, University of California, Davis, California.
Moshref M; Division of Cardiovascular Medicine, University of California, Davis, California.
Knowlton AA; Division of Cardiovascular Medicine, University of California, Davis, California; US Department of Veterans Affairs, Northern California Health Care System, Mather, California.
Sirish P; Division of Cardiovascular Medicine, University of California, Davis, California. Electronic address: psirish@ucdavis.edu.
Chiamvimonvat N; Division of Cardiovascular Medicine, University of California, Davis, California; US Department of Veterans Affairs, Northern California Health Care System, Mather, California. Electronic address: nchiamvimonvat@ucdavis.edu.

Heart Rhythm ; 14(11): 1685-1692, 2017 11.

Article em En | MEDLINE | ID: mdl-28668623

Assuntos

Terapia Genética/métodos; Cardiopatias/metabolismo; Células-Tronco Pluripotentes Induzidas/citologia; Miócitos Cardíacos/metabolismo; Fosfatidilinositol 3-Quinases/metabolismo; Animais; Diferenciação Celular; Movimento Celular; Células Cultivadas; Modelos Animais de Doenças; Fibroblastos/metabolismo; Fibroblastos/patologia; Cardiopatias/patologia; Masculino; Camundongos; Camundongos Knockout; Miócitos Cardíacos/patologia; Transdução de Sinais

Palavras-chave

Cardiac fibroblast; Cardiac progenitor cells; Electrotaxis; Human induced pluripotent stem cells; Phosphatidylinositide-3-kinase; Soluble vascular cell adhesion molecule

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Terapia Genética / Fosfatidilinositol 3-Quinases / Miócitos Cardíacos / Células-Tronco Pluripotentes Induzidas / Cardiopatias Idioma: En Ano de publicação: 2017 Tipo de documento: Article

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