Glucosylceramide and Glucosylsphingosine Quantitation by Liquid Chromatography-Tandem Mass Spectrometry to Enable In Vivo Preclinical Studies of Neuronopathic Gaucher Disease.

Hamler, Rick; Brignol, Nastry; Clark, Sean W; Morrison, Sean; Dungan, Leo B; Chang, Hui H; Khanna, Richie; Frascella, Michelle; Valenzano, Kenneth J; Benjamin, Elfrida R; Boyd, Robert E

Hamler, Rick; Brignol, Nastry; Clark, Sean W; Morrison, Sean; Dungan, Leo B; Chang, Hui H; Khanna, Richie; Frascella, Michelle; Valenzano, Kenneth J; Benjamin, Elfrida R; Boyd, Robert E.

Afiliação

Hamler R; Amicus Therapeutics, Inc. , 1 Cedar Brook Drive, Cranbury, New Jersey 08512, United States.
Brignol N; Amicus Therapeutics, Inc. , 1 Cedar Brook Drive, Cranbury, New Jersey 08512, United States.
Clark SW; Amicus Therapeutics, Inc. , 1 Cedar Brook Drive, Cranbury, New Jersey 08512, United States.
Morrison S; Amicus Therapeutics, Inc. , 1 Cedar Brook Drive, Cranbury, New Jersey 08512, United States.
Dungan LB; Amicus Therapeutics, Inc. , 1 Cedar Brook Drive, Cranbury, New Jersey 08512, United States.
Chang HH; Amicus Therapeutics, Inc. , 1 Cedar Brook Drive, Cranbury, New Jersey 08512, United States.
Khanna R; Amicus Therapeutics, Inc. , 1 Cedar Brook Drive, Cranbury, New Jersey 08512, United States.
Frascella M; Amicus Therapeutics, Inc. , 1 Cedar Brook Drive, Cranbury, New Jersey 08512, United States.
Valenzano KJ; Amicus Therapeutics, Inc. , 1 Cedar Brook Drive, Cranbury, New Jersey 08512, United States.
Benjamin ER; Amicus Therapeutics, Inc. , 1 Cedar Brook Drive, Cranbury, New Jersey 08512, United States.
Boyd RE; Amicus Therapeutics, Inc. , 1 Cedar Brook Drive, Cranbury, New Jersey 08512, United States.

Anal Chem ; 89(16): 8288-8295, 2017 08 15.

Article em En | MEDLINE | ID: mdl-28686011

Assuntos

Biomarcadores/análise; Doença de Gaucher/metabolismo; Glucosilceramidas/análise; Psicosina/análogos & derivados; Animais; Biomarcadores/metabolismo; Encéfalo/metabolismo; Cromatografia Líquida; Glucosilceramidase/antagonistas & inibidores; Glucosilceramidas/metabolismo; Camundongos Endogâmicos C57BL; Psicosina/análise; Psicosina/metabolismo; Espectrometria de Massas em Tandem; beta-Glucosidase/antagonistas & inibidores

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Psicosina / Biomarcadores / Doença de Gaucher / Glucosilceramidas Idioma: En Ano de publicação: 2017 Tipo de documento: Article

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