Pseudomonas aeruginosa quorum sensing modulates immune responses: An updated review article.

Kariminik, Ashraf; Baseri-Salehi, Majid; Kheirkhah, Babak

Kariminik, Ashraf; Baseri-Salehi, Majid; Kheirkhah, Babak.

Afiliação

Kariminik A; Department of Microbiology, Kerman Branch, Islamic Azad University, Kerman, Iran. Electronic address: a.kariminik@iauk.ac.ir.
Baseri-Salehi M; Department of Microbiology, Kazeroun Branch, Islamic Azad University, Kazeroun, Iran.
Kheirkhah B; Department of Microbiology, Kerman Branch, Islamic Azad University, Kerman, Iran.

Immunol Lett ; 190: 1-6, 2017 10.

Article em En | MEDLINE | ID: mdl-28698104

ABSTRACT

ABSTRACT

Pseudomonas aeruginosa is an opportunistic bacterium which induces some complications in immunocompromised patients. Pseudomonas aeruginosa is a quorum-sensing using bacterium which regulates its genes expression. The bacterium uses two famous pathways for quorum sensing entitled LasI/LasR and RhlI/RhlR systems. It has been documented that the bacteria which use quorum sensing are able to overcome immune responses. This review article aims to present recent information regarding the effects of Pseudomonas aeruginosa quorum sensing systems on the host immune responses.

Assuntos

Infecções por Pseudomonas/imunologia; Pseudomonas aeruginosa/imunologia; Percepção de Quorum; Animais; Proteínas de Bactérias/metabolismo; Subunidade RIIalfa da Proteína Quinase Dependente de AMP Cíclico/metabolismo; Regulação Bacteriana da Expressão Gênica; Humanos; Evasão da Resposta Imune; Imunidade Inata; Transativadores/metabolismo

Palavras-chave

3O-C12-HSL; C4-HSL; Immune system; Pseudomonas aeruginosa; Quorum sensing

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Pseudomonas aeruginosa / Infecções por Pseudomonas / Percepção de Quorum Idioma: En Ano de publicação: 2017 Tipo de documento: Article

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