Solvent-Driven Dynamical Crossover in the Phenylalanine Side-Chain from the Hydrophobic Core of Amyloid Fibrils Detected by <sup>2</sup>H NMR Relaxation.

Vugmeyster, Liliya; Ostrovsky, Dmitry; Hoatson, Gina L; Qiang, Wei; Falconer, Isaac B

Solvent-Driven Dynamical Crossover in the Phenylalanine Side-Chain from the Hydrophobic Core of Amyloid Fibrils Detected by ²H NMR Relaxation.

Vugmeyster, Liliya; Ostrovsky, Dmitry; Hoatson, Gina L; Qiang, Wei; Falconer, Isaac B.

Afiliação

Vugmeyster L; Department of Chemistry, University of Colorado at Denver , Denver, Colorado 80204, United States.
Ostrovsky D; Department of Mathematics, University of Colorado at Denver , Denver, Colorado 80204, United States.
Hoatson GL; Department of Physics, College of William and Mary , Williamsburg, Virginia 23187, United States.
Qiang W; Department of Chemistry, Binghamton University , Binghamton, New York 13902, United States.
Falconer IB; Department of Chemistry, University of Colorado at Denver , Denver, Colorado 80204, United States.

J Phys Chem B ; 121(30): 7267-7275, 2017 08 03.

Article em En | MEDLINE | ID: mdl-28699757

Assuntos

Amiloide/química; Ressonância Magnética Nuclear Biomolecular; Fenilalanina/química; Solventes/química; Sequência de Aminoácidos; Amiloide/genética; Amiloide/metabolismo; Peptídeos beta-Amiloides/química; Peptídeos beta-Amiloides/genética; Peptídeos beta-Amiloides/metabolismo; Interações Hidrofóbicas e Hidrofílicas; Modelos Moleculares; Mutagênese Sítio-Dirigida; Fragmentos de Peptídeos/química; Fragmentos de Peptídeos/genética; Fragmentos de Peptídeos/metabolismo; Temperatura

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Fenilalanina / Solventes / Ressonância Magnética Nuclear Biomolecular / Amiloide Idioma: En Ano de publicação: 2017 Tipo de documento: Article

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