Serum Fetuin-A Levels and Thyroid Function inMiddle-aged and Elderly Chinese.
Biomed Environ Sci
; 30(6): 455-459, 2017 Jun.
Article
em En
| MEDLINE
| ID: mdl-28705270
ABSTRACT
Serum fetuin-A levels are reportedly elevated in hyperthyroidism. However, there are few relevant epidemiologic studies. We conducted a cross-sectional study in Songnan community, China in 2009 to investigate the association between serum fetuin-A concentrations and thyroid function. A total of 2,984 participants aged 40 years and older were analyzed. Multivariable linear regression analysis revealed that serum fetuin-A concentra- tions were positively associated with log (free triiodothyronine) and were inversely associated with log (thyroid peroxidase antibody) after adjustment (both P < 0.05). Compared with the participants in the lowest tertile of free triiodo-thyronine and free thyroxine level, those in the highest tertile had higher fetuin-A concentrations. Additionally, high serum fetuin-A concentrations were related to high thyroid function (odds ratio 1.27, 95% confidence interval 1.01-1.61), after adjustment for conventional risk factors.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Povo Asiático
/
Alfa-2-Glicoproteína-HS
/
Hipertireoidismo
Idioma:
En
Ano de publicação:
2017
Tipo de documento:
Article