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Novel thiosemicarbazide derivatives with 4-nitrophenyl group as multi-target drugs: α-glucosidase inhibitors with antibacterial and antiproliferative activity.
Wos, Maciej; Miazga-Karska, Malgorzata; Kaczor, Agnieszka A; Klimek, Katarzyna; Karczmarzyk, Zbigniew; Kowalczuk, Dorota; Wysocki, Waldemar; Ginalska, Grazyna; Urbanczyk-Lipkowska, Zofia; Morawiak, Maja; Pitucha, Monika.
Afiliação
  • Wos M; Department of Organic Chemistry, Medical University, 4A Chodzki St., PL-20093, Lublin, Poland.
  • Miazga-Karska M; Department of Biochemistry and Biotechnology, Medical University,1 Chodzki St., PL-20093, Lublin, Poland.
  • Kaczor AA; Department of Synthesis and Chemical Technology of Pharmaceutical Substances with Computer Modeling Laboratory, Medical University,1 Chodzki St., PL-20093, Lublin, Poland; University of Eastern Finland, School of Pharmacy, Department of Pharmaceutical Chemistry, Yliopistonranta 1, P.O. Box 1627, FI-
  • Klimek K; Department of Biochemistry and Biotechnology, Medical University,1 Chodzki St., PL-20093, Lublin, Poland.
  • Karczmarzyk Z; Department of Chemistry, Siedlce University of Natural Sciences and Humanities, 3 Maja 54 St., PL-08110, Siedlce, Poland.
  • Kowalczuk D; Department of Medicinal Chemistry, Medical University of Lublin, Jaczewskiego 4 St., PL-20090, Lublin, Poland.
  • Wysocki W; Department of Chemistry, Siedlce University of Natural Sciences and Humanities, 3 Maja 54 St., PL-08110, Siedlce, Poland.
  • Ginalska G; Department of Biochemistry and Biotechnology, Medical University,1 Chodzki St., PL-20093, Lublin, Poland.
  • Urbanczyk-Lipkowska Z; Institute of Organic Chemistry, Polish Academy of Sciences,Kasprzaka 44/52 St., PL-01224, Warsaw, Poland.
  • Morawiak M; Institute of Organic Chemistry, Polish Academy of Sciences,Kasprzaka 44/52 St., PL-01224, Warsaw, Poland.
  • Pitucha M; Department of Organic Chemistry, Medical University, 4A Chodzki St., PL-20093, Lublin, Poland. Electronic address: monika.pitucha@umlub.pl.
Biomed Pharmacother ; 93: 1269-1276, 2017 Sep.
Article em En | MEDLINE | ID: mdl-28747001

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Semicarbazidas / Proliferação de Células / Inibidores de Glicosídeo Hidrolases / Antibacterianos / Nitrofenóis Idioma: En Ano de publicação: 2017 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Semicarbazidas / Proliferação de Células / Inibidores de Glicosídeo Hidrolases / Antibacterianos / Nitrofenóis Idioma: En Ano de publicação: 2017 Tipo de documento: Article