The emerging role and targetability of the TCA cycle in cancer metabolism.

Anderson, Nicole M; Mucka, Patrick; Kern, Joseph G; Feng, Hui

Anderson, Nicole M; Mucka, Patrick; Kern, Joseph G; Feng, Hui.

Afiliação

Anderson NM; Abramson Family Cancer Research Institute, University of Pennsylvania, Philadelphia, PA, 19104-6160, USA.
Mucka P; Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, 19104, USA.
Kern JG; Departments of Pharmacology and Medicine, The Center for Cancer Research, Section of Hematology and Medical Oncology, Boston University School of Medicine, Boston, MA, 02118, USA.
Feng H; Program in Biomedical Sciences, Boston University School of Medicine, Boston, MA, 02118, USA.

Protein Cell ; 9(2): 216-237, 2018 02.

Article em En | MEDLINE | ID: mdl-28748451

Assuntos

Ciclo do Ácido Cítrico/efeitos dos fármacos; Terapia de Alvo Molecular/métodos; Neoplasias/tratamento farmacológico; Neoplasias/metabolismo; Animais; Humanos; Neoplasias/genética; Neoplasias/patologia; Oncogenes/genética; Proteínas Supressoras de Tumor/metabolismo

Palavras-chave

cancer metabolism; glutaminolysis; glycolysis; the TCA cycle

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Ciclo do Ácido Cítrico / Terapia de Alvo Molecular / Neoplasias Idioma: En Ano de publicação: 2018 Tipo de documento: Article

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