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Pharmacogenetic meta-analysis of baseline risk factors, pharmacodynamic, efficacy and tolerability endpoints from two large global cardiovascular outcomes trials for darapladib.
Yeo, Astrid; Li, Li; Warren, Liling; Aponte, Jennifer; Fraser, Dana; King, Karen; Johansson, Kelley; Barnes, Allison; MacPhee, Colin; Davies, Richard; Chissoe, Stephanie; Tarka, Elizabeth; O'Donoghue, Michelle L; White, Harvey D; Wallentin, Lars; Waterworth, Dawn.
Afiliação
  • Yeo A; Department of Genetics, GlaxoSmithKline Medicines Research Centre, Stevenage, Hertfordshire, United Kingdom.
  • Li L; Department of Genetics, GlaxoSmithKline Medicines Research Centre, Research Triangle Park, North Carolina, United States of America.
  • Warren L; Department of Genetics, GlaxoSmithKline Medicines Research Centre, Research Triangle Park, North Carolina, United States of America.
  • Aponte J; Department of Genetics, GlaxoSmithKline Medicines Research Centre, Research Triangle Park, North Carolina, United States of America.
  • Fraser D; Department of Genetics, GlaxoSmithKline Medicines Research Centre, Research Triangle Park, North Carolina, United States of America.
  • King K; Department of Genetics, GlaxoSmithKline Medicines Research Centre, Research Triangle Park, North Carolina, United States of America.
  • Johansson K; Department of Genetics, GlaxoSmithKline Medicines Research Centre, Research Triangle Park, North Carolina, United States of America.
  • Barnes A; Clinical Statistics, GlaxoSmithKline Medicines Research Centre, Research Triangle Park, North Carolina, United States of America.
  • MacPhee C; Department of Vascular Biology & Thrombosis, GlaxoSmithKline Medicines Research Centre, King of Prussia, Pennsylvania, United States of America.
  • Davies R; Metabolic Pathways and Cardiovascular Therapeutic Area, GlaxoSmithKline Medicines Research Centre, King of Prussia, Pennsylvania, United States of America.
  • Chissoe S; Department of Genetics, GlaxoSmithKline Medicines Research Centre, Research Triangle Park, North Carolina, United States of America.
  • Tarka E; Metabolic Pathways and Cardiovascular Therapeutic Area, GlaxoSmithKline Medicines Research Centre, King of Prussia, Pennsylvania, United States of America.
  • O'Donoghue ML; TIMI Study Group, Cardiovascular Division, Brigham and Women's Hospital, Boston, Massachusetts, United States of America.
  • White HD; Green Lane Cardiovascular Service, Auckland City Hospital and University of Auckland, Auckland, New Zealand.
  • Wallentin L; Department of Medical Sciences, Cardiology & Uppsala Clinical Research Center, Uppsala University, Uppsala, Sweden.
  • Waterworth D; Department of Genetics, GlaxoSmithKline Medicines Research Centre, Upper Merion, Philadelphia, Pennsylvania, United States of America.
PLoS One ; 12(7): e0182115, 2017.
Article em En | MEDLINE | ID: mdl-28753643
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Oximas / Benzaldeídos Idioma: En Ano de publicação: 2017 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Oximas / Benzaldeídos Idioma: En Ano de publicação: 2017 Tipo de documento: Article