Effect of Aspirin and ibuprofen either alone or in combination on gastric mucosa and bleeding time and on serum prostaglandin E<sub>2</sub> and thromboxane A<sub>2</sub> levels in the anaesthetized rats in vivo.

Bastaki, Salim M A; Padol, Ireneusz T; Amir, Naheed; Hunt, Richard H

Effect of Aspirin and ibuprofen either alone or in combination on gastric mucosa and bleeding time and on serum prostaglandin E₂ and thromboxane A₂ levels in the anaesthetized rats in vivo.

Bastaki, Salim M A; Padol, Ireneusz T; Amir, Naheed; Hunt, Richard H.

Afiliação

Bastaki SMA; Department of Pharmacology, Faculty of Medicine and Health Sciences, UAE University, Twam Street, P.O. Box 17666, Al Ain, UAE. sbastaki@uaeu.ac.ae.
Padol IT; Division of Gastroenterology, McMaster University, Hamilton, ON, Canada.
Amir N; Department of Pharmacology, Faculty of Medicine and Health Sciences, UAE University, Twam Street, P.O. Box 17666, Al Ain, UAE.
Hunt RH; Division of Gastroenterology, McMaster University, Hamilton, ON, Canada.

Mol Cell Biochem ; 438(1-2): 25-34, 2018 Jan.

Article em En | MEDLINE | ID: mdl-28766164

Assuntos

Aspirina; Dinoprostona/sangue; Mucosa Gástrica/metabolismo; Ibuprofeno; Úlcera Gástrica; Tromboxano A2/sangue; Anestesia; Animais; Aspirina/efeitos adversos; Aspirina/farmacocinética; Tempo de Sangramento; Feminino; Mucosa Gástrica/patologia; Ibuprofeno/efeitos adversos; Ibuprofeno/farmacologia; Masculino; Ratos; Ratos Wistar; Úlcera Gástrica/sangue; Úlcera Gástrica/induzido quimicamente; Úlcera Gástrica/patologia

Palavras-chave

Bleeding time; NSAIDS; Rat; Stomach; Thromboxane A2 and prostaglandin E2; Ulcer

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Úlcera Gástrica / Tromboxano A2 / Dinoprostona / Aspirina / Ibuprofeno / Mucosa Gástrica Idioma: En Ano de publicação: 2018 Tipo de documento: Article

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