Functional genomic exploration reveals that Ss-RIOK-1 is essential for the development and survival of Strongyloides stercoralis larvae.

Yuan, Wang; Zhou, Huan; Lok, James B; Lei, Weiqiang; He, Siyuan; Gasser, Robin B; Zhou, Rui; Fang, Rui; Zhou, Yanqin; Zhao, Junlong; Hu, Min

Yuan, Wang; Zhou, Huan; Lok, James B; Lei, Weiqiang; He, Siyuan; Gasser, Robin B; Zhou, Rui; Fang, Rui; Zhou, Yanqin; Zhao, Junlong; Hu, Min.

Afiliação

Yuan W; State Key Laboratory of Agricultural Microbiology, College of Veterinary Medicine, Huazhong Agricultural University, Wuhan, China.
Zhou H; State Key Laboratory of Agricultural Microbiology, College of Veterinary Medicine, Huazhong Agricultural University, Wuhan, China.
Lok JB; Department of Pathobiology, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, PA, United States.
Lei W; State Key Laboratory of Agricultural Microbiology, College of Veterinary Medicine, Huazhong Agricultural University, Wuhan, China.
He S; State Key Laboratory of Agricultural Microbiology, College of Veterinary Medicine, Huazhong Agricultural University, Wuhan, China.
Gasser RB; State Key Laboratory of Agricultural Microbiology, College of Veterinary Medicine, Huazhong Agricultural University, Wuhan, China; Faculty of Veterinary and Agricultural Sciences, The University of Melbourne, Parkville, Victoria, Australia.
Zhou R; State Key Laboratory of Agricultural Microbiology, College of Veterinary Medicine, Huazhong Agricultural University, Wuhan, China.
Fang R; State Key Laboratory of Agricultural Microbiology, College of Veterinary Medicine, Huazhong Agricultural University, Wuhan, China.
Zhou Y; State Key Laboratory of Agricultural Microbiology, College of Veterinary Medicine, Huazhong Agricultural University, Wuhan, China.
Zhao J; State Key Laboratory of Agricultural Microbiology, College of Veterinary Medicine, Huazhong Agricultural University, Wuhan, China.
Hu M; State Key Laboratory of Agricultural Microbiology, College of Veterinary Medicine, Huazhong Agricultural University, Wuhan, China. Electronic address: mhu@mail.hzau.edu.cn.

Int J Parasitol ; 47(14): 933-940, 2017 12.

Article em En | MEDLINE | ID: mdl-28780152

Assuntos

Proteínas Quinases/fisiologia; Strongyloides stercoralis/crescimento & desenvolvimento; Trifosfato de Adenosina/metabolismo; Animais; Animais Geneticamente Modificados/genética; Animais Geneticamente Modificados/crescimento & desenvolvimento; Citoplasma/enzimologia; Cães; Feminino; Expressão Gênica; Larva/enzimologia; Larva/genética; Larva/crescimento & desenvolvimento; Masculino; Mutação; Fenótipo; Inibidores de Proteínas Quinases/farmacologia; Proteínas Quinases/genética; Proteínas Quinases/metabolismo; Strongyloides stercoralis/enzimologia; Strongyloides stercoralis/genética; Transformação Genética; Transgenes

Palavras-chave

Development; Protein kinases; RIOK-1; Strongyloides stercoralis; Transgenesis

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Proteínas Quinases / Strongyloides stercoralis Idioma: En Ano de publicação: 2017 Tipo de documento: Article

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Proteínas Quinases / Strongyloides stercoralis Idioma: En Ano de publicação: 2017 Tipo de documento: Article