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Antitumor activity of ß-2-himachalen-6-ol in colon cancer is mediated through its inhibition of the PI3K and MAPK pathways.
Daaboul, Hamid E; Daher, Costantine F; Bodman-Smith, Kikki; Taleb, Robin I; Shebaby, Wassim N; Boulos, Joelle; Dagher, Carole; Mroueh, Mohamad A; El-Sibai, Mirvat.
Afiliação
  • Daaboul HE; Faculty of Health and Medical Sciences, Department of Microbial Sciences, University of Surrey, UK.
  • Daher CF; Department of Natural Sciences, School of Arts and Sciences, Lebanese American University, P.O. Box 36, Byblos, Lebanon.
  • Bodman-Smith K; Faculty of Health and Medical Sciences, Department of Microbial Sciences, University of Surrey, UK.
  • Taleb RI; Department of Natural Sciences, School of Arts and Sciences, Lebanese American University, P.O. Box 36, Byblos, Lebanon.
  • Shebaby WN; Department of Natural Sciences, School of Arts and Sciences, Lebanese American University, P.O. Box 36, Byblos, Lebanon.
  • Boulos J; Department of Natural Sciences, School of Arts and Sciences, Lebanese American University, P.O. Box 36, Byblos, Lebanon.
  • Dagher C; School of Medicine, Lebanese American University, Byblos, Lebanon.
  • Mroueh MA; School of Pharmacy, Department of Pharmaceutical Sciences, Lebanese American University, P.O. Box 36, Byblos, Lebanon.
  • El-Sibai M; Department of Natural Sciences, School of Arts and Sciences, Lebanese American University, P.O. Box 36, Byblos, Lebanon. Electronic address: mirvat.elsibai@lau.edu.lb.
Chem Biol Interact ; 275: 162-170, 2017 Sep 25.
Article em En | MEDLINE | ID: mdl-28782499

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Sesquiterpenos / Transdução de Sinais / Apoptose / Proteínas Proto-Oncogênicas c-akt / Inibidores de Fosfoinositídeo-3 Quinase / Antineoplásicos Fitogênicos Idioma: En Ano de publicação: 2017 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Sesquiterpenos / Transdução de Sinais / Apoptose / Proteínas Proto-Oncogênicas c-akt / Inibidores de Fosfoinositídeo-3 Quinase / Antineoplásicos Fitogênicos Idioma: En Ano de publicação: 2017 Tipo de documento: Article