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PEGylation of Lumbrokinase improves pharmacokinetic profile and enhances anti­thrombotic effect in a rat carotid artery thrombosis model.
Jin, Mingji; Jin, Guangming; Huang, Wei; Gao, Zhonggao.
Afiliação
  • Jin M; State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, P.R. China.
  • Jin G; Department of Diagnostic Radiology 2, Yanbian University Hospital, Yanji, Jilin 133000, P.R. China.
  • Huang W; State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, P.R. China.
  • Gao Z; State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, P.R. China.
Mol Med Rep ; 16(4): 4909-4914, 2017 Oct.
Article em En | MEDLINE | ID: mdl-28791355
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Endopeptidases / Polietilenoglicóis / Trombose das Artérias Carótidas / Fibrinolíticos Idioma: En Ano de publicação: 2017 Tipo de documento: Article
Texto completo
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XML
PubMed Links
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Endopeptidases / Polietilenoglicóis / Trombose das Artérias Carótidas / Fibrinolíticos Idioma: En Ano de publicação: 2017 Tipo de documento: Article