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Structural basis for therapeutic inhibition of influenza A polymerase PB2 subunit.
Ma, Xiaolei; Xie, Lili; Wartchow, Charles; Warne, Robert; Xu, Yongjin; Rivkin, Alexey; Tully, David; Shia, Steven; Uehara, Kyoko; Baldwin, Dianna M; Muiru, Gladys; Zhong, Weidong; Zaror, Isabel; Bussiere, Dirksen E; Leonard, Vincent H J.
Afiliação
  • Ma X; Structural and Biophysical Chemistry, Novartis Institutes for BioMedical Research, Emeryville, CA, USA. xiaolei.ma@novartis.com.
  • Xie L; Global Discovery Chemistry, Novartis Institutes for BioMedical Research, Emeryville, CA, USA. xiaolei.ma@novartis.com.
  • Wartchow C; Protein Sciences, Novartis Institutes for BioMedical Research, Emeryville, CA, USA.
  • Warne R; Structural and Biophysical Chemistry, Novartis Institutes for BioMedical Research, Emeryville, CA, USA.
  • Xu Y; Global Discovery Chemistry, Novartis Institutes for BioMedical Research, Emeryville, CA, USA.
  • Rivkin A; Virology Lead Discovery, Novartis Institutes for BioMedical Research, Emeryville, CA, USA.
  • Tully D; Global Discovery Chemistry, Novartis Institutes for BioMedical Research, Emeryville, CA, USA.
  • Shia S; Global Discovery Chemistry, Novartis Institutes for BioMedical Research, Emeryville, CA, USA.
  • Uehara K; Global Discovery Chemistry, Novartis Institutes for BioMedical Research, Emeryville, CA, USA.
  • Baldwin DM; Structural and Biophysical Chemistry, Novartis Institutes for BioMedical Research, Emeryville, CA, USA.
  • Muiru G; Protein Sciences, Novartis Institutes for BioMedical Research, Emeryville, CA, USA.
  • Zhong W; Virology, Novartis Institutes for BioMedical Research, Emeryville, CA, USA.
  • Zaror I; Virology, Novartis Institutes for BioMedical Research, Emeryville, CA, USA.
  • Bussiere DE; Virology, Novartis Institutes for BioMedical Research, Emeryville, CA, USA.
  • Leonard VHJ; Protein Sciences, Novartis Institutes for BioMedical Research, Emeryville, CA, USA.
Sci Rep ; 7(1): 9385, 2017 08 24.
Article em En | MEDLINE | ID: mdl-28839261
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Antivirais / Vírus da Influenza A / RNA Polimerase Dependente de RNA / Subunidades Proteicas Idioma: En Ano de publicação: 2017 Tipo de documento: Article
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Antivirais / Vírus da Influenza A / RNA Polimerase Dependente de RNA / Subunidades Proteicas Idioma: En Ano de publicação: 2017 Tipo de documento: Article