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Characterizing the in vitro species differences in N-glucuronidation of a potent pan-PIM inhibitor GNE-924 containing a 3,5-substituted 6-azaindazole.
Lin, Molly; Ly, Justin; Takahashi, Ryan; Chen, John; Deese, Alan; Robinson, Sarah J; Kolesnikov, Aleksandr; Wong, Susan; Wang, Xiaojing; Chang, Jae H.
Afiliação
  • Lin M; a Department of Drug Metabolism and Pharmacokinetics, Genentech , South San Francisco , CA , USA.
  • Ly J; a Department of Drug Metabolism and Pharmacokinetics, Genentech , South San Francisco , CA , USA.
  • Takahashi R; a Department of Drug Metabolism and Pharmacokinetics, Genentech , South San Francisco , CA , USA.
  • Chen J; a Department of Drug Metabolism and Pharmacokinetics, Genentech , South San Francisco , CA , USA.
  • Deese A; a Department of Drug Metabolism and Pharmacokinetics, Genentech , South San Francisco , CA , USA.
  • Robinson SJ; a Department of Drug Metabolism and Pharmacokinetics, Genentech , South San Francisco , CA , USA.
  • Kolesnikov A; a Department of Drug Metabolism and Pharmacokinetics, Genentech , South San Francisco , CA , USA.
  • Wong S; a Department of Drug Metabolism and Pharmacokinetics, Genentech , South San Francisco , CA , USA.
  • Wang X; a Department of Drug Metabolism and Pharmacokinetics, Genentech , South San Francisco , CA , USA.
  • Chang JH; a Department of Drug Metabolism and Pharmacokinetics, Genentech , South San Francisco , CA , USA.
Xenobiotica ; 48(10): 1021-1027, 2018 Oct.
Article em En | MEDLINE | ID: mdl-28845725
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Antivirais / Piperazinas / Pirazóis / Piridinas / Glucuronídeos / Indazóis / Vírus da Leucemia Murina de Moloney Idioma: En Ano de publicação: 2018 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Antivirais / Piperazinas / Pirazóis / Piridinas / Glucuronídeos / Indazóis / Vírus da Leucemia Murina de Moloney Idioma: En Ano de publicação: 2018 Tipo de documento: Article