Your browser doesn't support javascript.
loading
Hybrid localized surface plasmon resonance and quartz crystal microbalance sensor for label free biosensing.
Hao, Danni; Hu, Chunxiao; Grant, James; Glidle, Andrew; Cumming, David R S.
Afiliação
  • Hao D; School of Engineering, Rankine Building, University of Glasgow, Glasgow G12 8LT, UK. Electronic address: d.hao.1@research.gla.ac.uk.
  • Hu C; School of Engineering, Rankine Building, University of Glasgow, Glasgow G12 8LT, UK.
  • Grant J; School of Engineering, Rankine Building, University of Glasgow, Glasgow G12 8LT, UK.
  • Glidle A; School of Engineering, Rankine Building, University of Glasgow, Glasgow G12 8LT, UK.
  • Cumming DRS; School of Engineering, Rankine Building, University of Glasgow, Glasgow G12 8LT, UK. Electronic address: david.cumming.2@glasgow.ac.uk.
Biosens Bioelectron ; 100: 23-27, 2018 Feb 15.
Article em En | MEDLINE | ID: mdl-28850824
ABSTRACT
We report on the design and fabrication of a hybrid sensor that integrates transmission-mode localized surface plasmonic resonance (LSPR) into a quartz crystal microbalance (QCM) for studying biochemical surface reactions. The coupling of LSPR nanostructures and a QCM allows optical spectra and QCM resonant frequency shifts to be recorded simultaneously and analyzed in real time for a given surface adsorption process. This integration simplifies the conventional combination of SPR and QCM and has the potential to be miniaturized for application in point-of-care (POC) diagnostics. The influence of antibody-antigen recognition effect on both the QCM and LSPR has been analyzed and discussed.
Assuntos
Palavras-chave

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Imunoglobulina G / Ressonância de Plasmônio de Superfície / Anticorpos Imobilizados / Técnicas de Microbalança de Cristal de Quartzo Idioma: En Ano de publicação: 2018 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Imunoglobulina G / Ressonância de Plasmônio de Superfície / Anticorpos Imobilizados / Técnicas de Microbalança de Cristal de Quartzo Idioma: En Ano de publicação: 2018 Tipo de documento: Article