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20(S)-25-methoxyl-dammarane-3ß, 12ß, 20-triol negatively regulates activation of STAT3 and ERK pathways and exhibits anti-cancer effects in HepG2 cells.
Ai, Hui-Han; Zhou, Zi-Long; Sun, Lu-Guo; Yang, Mei-Ting; Li, Wei; Yu, Chun-Lei; Song, Zhen-Bo; Huang, Yan-Xin; Wu, Yin; Liu, Lei; Yang, Xiao-Guang; Zhao, Yu-Qing; Bao, Yong-Li; Li, Yu-Xin.
Afiliação
  • Ai HH; National Engineering Laboratory for Druggable Gene and Protein Screening, Northeast Normal University, Changchun, 130024, China.
  • Zhou ZL; National Engineering Laboratory for Druggable Gene and Protein Screening, Northeast Normal University, Changchun, 130024, China.
  • Sun LG; National Engineering Laboratory for Druggable Gene and Protein Screening, Northeast Normal University, Changchun, 130024, China. sunlg388@nenu.edu.cn.
  • Yang MT; National Engineering Laboratory for Druggable Gene and Protein Screening, Northeast Normal University, Changchun, 130024, China.
  • Li W; Key Laboratory of Structure-based Drug Design & Discovery, Ministry of Education, Shenyang Pharmaceutical University, Shenyang, 110016, China.
  • Yu CL; Institute of Genetics and Cytology, Northeast Normal University, Changchun, 130024, China.
  • Song ZB; National Engineering Laboratory for Druggable Gene and Protein Screening, Northeast Normal University, Changchun, 130024, China.
  • Huang YX; National Engineering Laboratory for Druggable Gene and Protein Screening, Northeast Normal University, Changchun, 130024, China.
  • Wu Y; Institute of Genetics and Cytology, Northeast Normal University, Changchun, 130024, China.
  • Liu L; Institute of Genetics and Cytology, Northeast Normal University, Changchun, 130024, China.
  • Yang XG; National Engineering Laboratory for Druggable Gene and Protein Screening, Northeast Normal University, Changchun, 130024, China.
  • Zhao YQ; Key Laboratory of Structure-based Drug Design & Discovery, Ministry of Education, Shenyang Pharmaceutical University, Shenyang, 110016, China. zyq4885@126.com.
  • Bao YL; National Engineering Laboratory for Druggable Gene and Protein Screening, Northeast Normal University, Changchun, 130024, China. baoyl800@nenu.edu.cn.
  • Li YX; Institute of Genetics and Cytology, Northeast Normal University, Changchun, 130024, China.
Apoptosis ; 22(11): 1404-1418, 2017 Nov.
Article em En | MEDLINE | ID: mdl-28864870
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Regulação Neoplásica da Expressão Gênica / Hepatoblastoma / Ginsenosídeos / Fator de Transcrição STAT3 / Neoplasias Hepáticas / Antineoplásicos Fitogênicos Idioma: En Ano de publicação: 2017 Tipo de documento: Article
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Regulação Neoplásica da Expressão Gênica / Hepatoblastoma / Ginsenosídeos / Fator de Transcrição STAT3 / Neoplasias Hepáticas / Antineoplásicos Fitogênicos Idioma: En Ano de publicação: 2017 Tipo de documento: Article