Cutaneous alternariosis in an immunocompromised dog successfully treated with cold plasma and cessation of immunosuppressive medication.
Tierarztl Prax Ausg K Kleintiere Heimtiere
; 45(5): 337-343, 2017 Oct 17.
Article
em En
| MEDLINE
| ID: mdl-28905976
ABSTRACT
A cutaneous infection with Alternaria spp. was diagnosed in a 2-year-old male intact Irish setter dog, presenting with multifocal papules, plaques and ulcerations involving all four distal limbs, shoulder blades, scrotum, pinnae and nasal mucous membranes. The dog had been treated for inflammatory bowel disease and lymphangiectasia with immunosuppressive doses of cyclosporine and prednisolone for approximately 3 months. The diagnosis was based on clinical signs, the demonstration of fungal elements within skin biopsies, deep fungal culture and fungal PCR from a formalin-fixed tissue specimen. Complete clinical remission was achieved by tapering and cessation of the immunosuppressive medication, treatment with cold atmospheric-pressure plasma (CAPP) and topical enilconazole within 8 weeks.
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Base de dados:
MEDLINE
Assunto principal:
Hospedeiro Imunocomprometido
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Doenças do Cão
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Gases em Plasma
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Alternariose
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Imunossupressores
Idioma:
En
Ano de publicação:
2017
Tipo de documento:
Article