Cortisol awakening response in patients with bipolar disorder during acute episodes and partial remission: A pilot study.
Psychiatry Res
; 258: 594-597, 2017 12.
Article
em En
| MEDLINE
| ID: mdl-28911851
ABSTRACT
This exploratory study examined the cortisol awakening response (CAR) in patients with bipolar disorder (BPD) at acute phases and partial remission of manic or depressive episodes. Saliva samples of twenty-seven BPD inpatients and 25 healthy controls were collected to determine the CAR patterns, and 12 patients were sampled again at partial remission. BPD patients exhibited a non-enhanced CAR pattern. Lower cortisol expression and a blunted CAR distinguished bipolar-depressive patients from the controls. The intra-individual follow-up for both patient groups revealed a non-significant improvement in CAR patterns, indicating a trend of a normalized CAR after partial remission for BPD patients.
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Texto completo:
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Base de dados:
MEDLINE
Assunto principal:
Vigília
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Transtorno Bipolar
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Hidrocortisona
Idioma:
En
Ano de publicação:
2017
Tipo de documento:
Article