Maternal plasma LPCAT 1 mRNA correlates with lamellar body count.
J Perinat Med
; 46(4): 429-431, 2018 May 24.
Article
em En
| MEDLINE
| ID: mdl-28926341
ABSTRACT
Human lysophosphatidylcholine acyltransferase 1 (hLPCAT1) is a protein which helps produce surfactant in the fetal lung. We previously reported that levels of cell-free fetal mRNA for hLPCAT1 in amniotic fluid are correlated with lamellar body count (LBC) (r2=0.93). This short communication demonstrates that fetal hLPCAT1 mRNA is also present in maternal blood. Its quantity also correlates with amniotic fluid LBC (r2=0.81). Research in maternal plasma hLPCAT1 may assist in understanding fetal and placental maturational processes.
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Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Maturidade dos Órgãos Fetais
/
1-Acilglicerofosfocolina O-Aciltransferase
Idioma:
En
Ano de publicação:
2018
Tipo de documento:
Article