Effect of GRP119 Receptor Agonist, Compound MBX-2982, on Activity of Human Glucokinase.
Bull Exp Biol Med
; 163(5): 695-698, 2017 Sep.
Article
em En
| MEDLINE
| ID: mdl-28944428
ABSTRACT
Validation of the method for studies of glucokinase activators by the spectrophotometric method in an in vitro test system is carried out. The advantage of NAD coenzyme vs. thio-NAD is proven. Manifest activation of glucokinase by MBX-2982 compound (GPR119 agonist) in a wide range of concentrations is demonstrated experimentally.
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Base de dados:
MEDLINE
Assunto principal:
Tetrazóis
/
Tiazóis
/
Glucoquinase
Idioma:
En
Ano de publicação:
2017
Tipo de documento:
Article