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Extra-mitochondrial prosurvival BCL-2 proteins regulate gene transcription by inhibiting the SUFU tumour suppressor.
Wu, Xiaofeng; Zhang, Li-Shu; Toombs, Jason; Kuo, Yi-Chun; Piazza, John Tyler; Tuladhar, Rubina; Barrett, Quinn; Fan, Chih-Wei; Zhang, Xuewu; Walensky, Loren D; Kool, Marcel; Cheng, Steven Y; Brekken, Rolf; Opferman, Joseph T; Green, Douglas R; Moldoveanu, Tudor; Lum, Lawrence.
Afiliação
  • Wu X; Department of Cell Biology, University of Texas Southwestern Medical Center, Dallas, Texas 75390, USA.
  • Zhang LS; Department of Cell Biology, University of Texas Southwestern Medical Center, Dallas, Texas 75390, USA.
  • Toombs J; Department of Surgery, University of Texas Southwestern Medical Center, Dallas, Texas 75390, USA.
  • Kuo YC; Department of Pharmacology, University of Texas Southwestern Medical Center, Dallas, Texas 75390, USA.
  • Piazza JT; Department of Pharmacology, University of Texas Southwestern Medical Center, Dallas, Texas 75390, USA.
  • Tuladhar R; Department of Biochemistry, University of Texas Southwestern Medical Center, Dallas, Texas 75390, USA.
  • Barrett Q; Department of Cell Biology, University of Texas Southwestern Medical Center, Dallas, Texas 75390, USA.
  • Fan CW; Department of Cell Biology, University of Texas Southwestern Medical Center, Dallas, Texas 75390, USA.
  • Zhang X; Department of Cell Biology, University of Texas Southwestern Medical Center, Dallas, Texas 75390, USA.
  • Walensky LD; Department of Cell Biology, University of Texas Southwestern Medical Center, Dallas, Texas 75390, USA.
  • Kool M; Department of Pharmacology, University of Texas Southwestern Medical Center, Dallas, Texas 75390, USA.
  • Cheng SY; Department of Biochemistry, University of Texas Southwestern Medical Center, Dallas, Texas 75390, USA.
  • Brekken R; Department of Pediatric Oncology, Dana Farber Cancer Institute, Boston, Massachusetts 02215, USA.
  • Opferman JT; Department of Pediatrics, Harvard Medical School, 450 Brookline Avenue, Boston, Massachusetts 02215, USA.
  • Green DR; Division of Pediatric Neurooncology, German Cancer Research Center (DKFZ), Im Neuenheimer Feld 280, Heidelberg 69120, Germany.
  • Moldoveanu T; German Cancer Consortium (DKTK), Core Center Heidelberg, 69120 Heidelberg, Germany.
  • Lum L; Department of Developmental Genetics, Nanjing Medical University, 140 Hanzhong Road, Nanjing, Jiangsu 210029, China.
Nat Cell Biol ; 19(10): 1226-1236, 2017 Oct.
Article em En | MEDLINE | ID: mdl-28945232

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Proteínas Repressoras / Transcrição Gênica / Proteínas Proto-Oncogênicas c-bcl-2 / Proteínas Supressoras de Tumor / Neoplasias Idioma: En Ano de publicação: 2017 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Proteínas Repressoras / Transcrição Gênica / Proteínas Proto-Oncogênicas c-bcl-2 / Proteínas Supressoras de Tumor / Neoplasias Idioma: En Ano de publicação: 2017 Tipo de documento: Article