Skp2-Mediated Stabilization of MTH1 Promotes Survival of Melanoma Cells upon Oxidative Stress.

Wang, Jia Yu; Liu, Guang Zhi; Wilmott, James S; La, Ting; Feng, Yu Chen; Yari, Hamed; Yan, Xu Guang; Thorne, Rick F; Scolyer, Richard A; Zhang, Xu Dong; Jin, Lei

Wang, Jia Yu; Liu, Guang Zhi; Wilmott, James S; La, Ting; Feng, Yu Chen; Yari, Hamed; Yan, Xu Guang; Thorne, Rick F; Scolyer, Richard A; Zhang, Xu Dong; Jin, Lei.

Afiliação

Wang JY; Translational Research Institute, Henan Provincial People's Hospital, Henan, China.
Liu GZ; School of Biomedical Sciences and Pharmacy, The University of Newcastle, New South Wales, Australia.
Wilmott JS; Translational Research Institute, Henan Provincial People's Hospital, Henan, China.
La T; Discipline of Pathology, The University of Sydney, and Tissue Pathology and Diagnostic Oncology, Royal Prince Alfred Hospital, Sydney, New South Wales, Australia.
Feng YC; School of Biomedical Sciences and Pharmacy, The University of Newcastle, New South Wales, Australia.
Yari H; School of Biomedical Sciences and Pharmacy, The University of Newcastle, New South Wales, Australia.
Yan XG; School of Biomedical Sciences and Pharmacy, The University of Newcastle, New South Wales, Australia.
Thorne RF; School of Biomedical Sciences and Pharmacy, The University of Newcastle, New South Wales, Australia.
Scolyer RA; Translational Research Institute, Henan Provincial People's Hospital, Henan, China.
Zhang XD; School of Environmental and Life Sciences, The University of Newcastle, New South Wales, Australia.
Jin L; Discipline of Pathology, The University of Sydney, and Tissue Pathology and Diagnostic Oncology, Royal Prince Alfred Hospital, Sydney, New South Wales, Australia.

Cancer Res ; 77(22): 6226-6239, 2017 11 15.

Article em En | MEDLINE | ID: mdl-28947420

Assuntos

Enzimas Reparadoras do DNA/genética; Melanoma/genética; Estresse Oxidativo; Monoéster Fosfórico Hidrolases/genética; Proteínas Quinases Associadas a Fase S/genética; Western Blotting; Linhagem Celular; Linhagem Celular Tumoral; Sobrevivência Celular/genética; Enzimas Reparadoras do DNA/metabolismo; Regulação Neoplásica da Expressão Gênica; Humanos; Sistema de Sinalização das MAP Quinases/genética; Melanoma/metabolismo; Melanoma/patologia; Monoéster Fosfórico Hidrolases/metabolismo; Poliubiquitina/metabolismo; Estabilidade Proteica; Interferência de RNA; Reação em Cadeia da Polimerase Via Transcriptase Reversa; Proteínas Quinases Associadas a Fase S/metabolismo; Ubiquitinação

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Monoéster Fosfórico Hidrolases / Estresse Oxidativo / Enzimas Reparadoras do DNA / Proteínas Quinases Associadas a Fase S / Melanoma Idioma: En Ano de publicação: 2017 Tipo de documento: Article

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