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GRL-09510, a Unique P2-Crown-Tetrahydrofuranylurethane -Containing HIV-1 Protease Inhibitor, Maintains Its Favorable Antiviral Activity against Highly-Drug-Resistant HIV-1 Variants in vitro.
Amano, Masayuki; Miguel Salcedo-Gómez, Pedro; Yedidi, Ravikiran S; Delino, Nicole S; Nakata, Hirotomo; Venkateswara Rao, Kalapala; Ghosh, Arun K; Mitsuya, Hiroaki.
Afiliação
  • Amano M; Departments of Infectious Diseases and Hematology, Kumamoto University School of Medicine, Kumamoto, 860-8556, Japan.
  • Miguel Salcedo-Gómez P; Departments of Infectious Diseases and Hematology, Kumamoto University School of Medicine, Kumamoto, 860-8556, Japan.
  • Yedidi RS; Experimental Retrovirology Section, HIV and AIDS Malignancy Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, 20892, USA.
  • Delino NS; Department of Biochemistry, Faculty of Medicine, University of Toronto, Toronto, ON, Canada.
  • Nakata H; Experimental Retrovirology Section, HIV and AIDS Malignancy Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, 20892, USA.
  • Venkateswara Rao K; Departments of Infectious Diseases and Hematology, Kumamoto University School of Medicine, Kumamoto, 860-8556, Japan.
  • Ghosh AK; Departments of Chemistry and Medicinal Chemistry, Purdue University, West Lafayette, IN, 47907, USA.
  • Mitsuya H; Departments of Chemistry and Medicinal Chemistry, Purdue University, West Lafayette, IN, 47907, USA.
Sci Rep ; 7(1): 12235, 2017 09 25.
Article em En | MEDLINE | ID: mdl-28947797

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Antivirais / HIV-1 / Inibidores da Protease de HIV / Furanos Idioma: En Ano de publicação: 2017 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Antivirais / HIV-1 / Inibidores da Protease de HIV / Furanos Idioma: En Ano de publicação: 2017 Tipo de documento: Article