Up-regulation of <i>selenoprotein P</i> and <i>HIP/PAP</i> mRNAs in hepatocytes by intermittent hypoxia via down-regulation of miR-203.

Up-regulation of selenoprotein P and HIP/PAP mRNAs in hepatocytes by intermittent hypoxia via down-regulation of miR-203.

Uchiyama, Tomoko; Ota, Hiroyo; Itaya-Hironaka, Asako; Shobatake, Ryogo; Yamauchi, Akiyo; Sakuramoto-Tsuchida, Sumiyo; Makino, Mai; Kimura, Hiroshi; Takeda, Maiko; Ohbayashi, Chiho; Takasawa, Shin.

Afiliação

Uchiyama T; Department of Biochemistry, Nara Medical University, Kashihara 634-8521, Japan.
Ota H; Department of Diagnostic Pathology, Nara Medical University, Kashihara 634-8522, Japan.
Itaya-Hironaka A; Department of Biochemistry, Nara Medical University, Kashihara 634-8521, Japan.
Shobatake R; Second Department of Internal Medicine, Nara Medical University, 840 Shijo-cho, Kashihara 634-8522, Japan.
Yamauchi A; Department of Biochemistry, Nara Medical University, Kashihara 634-8521, Japan.
Sakuramoto-Tsuchida S; Department of Biochemistry, Nara Medical University, Kashihara 634-8521, Japan.
Makino M; Department of Biochemistry, Nara Medical University, Kashihara 634-8521, Japan.
Kimura H; Department of Biochemistry, Nara Medical University, Kashihara 634-8521, Japan.
Takeda M; Department of Biochemistry, Nara Medical University, Kashihara 634-8521, Japan.
Ohbayashi C; Second Department of Internal Medicine, Nara Medical University, 840 Shijo-cho, Kashihara 634-8522, Japan.
Takasawa S; Department of Diagnostic Pathology, Nara Medical University, Kashihara 634-8522, Japan.

Biochem Biophys Rep ; 11: 130-137, 2017 Sep.

Article em En | MEDLINE | ID: mdl-28955777

Palavras-chave

AHSG, α2 HS-glycoprotein; ANGPTL6, angiopoietin-related growth factor; DICER, endoribonuclease Dicer; DROSHA, ribonuclease type III; ELISA, enzyme-linked immunosorbent assay; FCS, fetal calf serum; FGF21, fibroblast growth factor 21; HIP/PAP; HIP/PAP, hepatocarcinoma-intestine-pancreas/pancreatitis-associated protein; Hepatokine; IH, intermittent hypoxia; Intermittent hypoxia; LECT2, leukocyte cell-derived chemotaxin 2; MCPIP1, monocyte chemotactic protein-induced protein 1; REG family gene; Reg, regenerating gene; Rig, rat insulinoma gene; RpS15, ribosomal protein S15; SAS, sleep apnea syndrome; SELENOP; SELENOP, selenoprotein P; SHBG, sex hormone-binding globulin; TP63, transformation-related protein 63; WST-8, 2-(2-methoxy-4-nitrophenyl)−3-(4-nitrophenyl)−5-(2,4-disulfophenyl)−2H-tetrazolium monosodium salt; miR-203; miRNA, micro RNA; siRNA, small interfering RNA

Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2017 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2017 Tipo de documento: Article