Chondroitin sulfate proteoglycans from salmon nasal cartilage inhibit angiogenesis.

Kobayashi, Takashi; Kakizaki, Ikuko; Nozaka, Hiroyuki; Nakamura, Toshiya.

Afiliação

Kobayashi T; Department of Glycotechnology, Center for Advanced Medical Research, Graduate School of Medicine, Hirosaki University, 5 Zaifu-cho, Hirosaki, Aomori 036-8562, Japan.
Kakizaki I; Departments of Bioscience and Laboratory Medicine, Hirosaki University Graduate School of Health Sciences, 66-1 Hon-cho, Hirosaki, Aomori 036-8564, Japan.
Nozaka H; Department of Glycotechnology, Center for Advanced Medical Research, Graduate School of Medicine, Hirosaki University, 5 Zaifu-cho, Hirosaki, Aomori 036-8562, Japan.
Nakamura T; Departments of Bioscience and Laboratory Medicine, Hirosaki University Graduate School of Health Sciences, 66-1 Hon-cho, Hirosaki, Aomori 036-8564, Japan.

Biochem Biophys Rep ; 9: 72-78, 2017 Mar.

Article em En | MEDLINE | ID: mdl-28955991

Palavras-chave

Aggrecan; Angiogenesis; BME, basement membrane extract; BSA, bovine serum albumin; CAM, chorioallantoic membrane; CS, chondroitin sulfate; CSPG, chondroitin sulfate proteoglycan; Chondroitin sulfate proteoglycan; ECM, extracellular matrix; FAK, focal adhesion kinase; FBS, fetal bovine serum; GAG, glycosaminoglycan; GAPDH, glyceraldehyde-3-phosphate dehydrogenase; GalNAc, N-acetylgalactosamine; GdnHCl, guanidine hydrochloride; GlcUA, glucuronic acid; Glycosaminoglycan; HSPG, heparan sulfate proteoglycan; KSPG, keratin sulfate proteoglycan; MMP, matrix metalloproteinase; Matrix metalloproteinase; OA, osteoarthritis; PBS, phosphate-buffered saline; PG, proteoglycan; UA, uronic acid; Vascular endothelial cell

Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2017 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2017 Tipo de documento: Article