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Blood-derived macrophages prone to accumulate lysosomal lipids trigger oxLDL-dependent murine hepatic inflammation.
Houben, Tom; Oligschlaeger, Yvonne; Bitorina, Albert V; Hendrikx, Tim; Walenbergh, Sofie M A; Lenders, Marie-Hélène; Gijbels, Marion J J; Verheyen, Fons; Lütjohann, Dieter; Hofker, Marten H; Binder, Christoph J; Shiri-Sverdlov, Ronit.
Afiliação
  • Houben T; Departments of Molecular Genetics, Molecular Cell Biology and Electron Microscopy, School of Nutrition and Translational Research in Metabolism (NUTRIM), University of Maastricht; Universiteitssingel 50, ER 6229 ER, Maastricht, The Netherlands.
  • Oligschlaeger Y; Departments of Molecular Genetics, Molecular Cell Biology and Electron Microscopy, School of Nutrition and Translational Research in Metabolism (NUTRIM), University of Maastricht; Universiteitssingel 50, ER 6229 ER, Maastricht, The Netherlands.
  • Bitorina AV; Departments of Molecular Genetics, Molecular Cell Biology and Electron Microscopy, School of Nutrition and Translational Research in Metabolism (NUTRIM), University of Maastricht; Universiteitssingel 50, ER 6229 ER, Maastricht, The Netherlands.
  • Hendrikx T; Departments of Molecular Genetics, Molecular Cell Biology and Electron Microscopy, School of Nutrition and Translational Research in Metabolism (NUTRIM), University of Maastricht; Universiteitssingel 50, ER 6229 ER, Maastricht, The Netherlands.
  • Walenbergh SMA; Departments of Molecular Genetics, Molecular Cell Biology and Electron Microscopy, School of Nutrition and Translational Research in Metabolism (NUTRIM), University of Maastricht; Universiteitssingel 50, ER 6229 ER, Maastricht, The Netherlands.
  • Lenders MH; Departments of Molecular Genetics, Molecular Cell Biology and Electron Microscopy, School of Nutrition and Translational Research in Metabolism (NUTRIM), University of Maastricht; Universiteitssingel 50, ER 6229 ER, Maastricht, The Netherlands.
  • Gijbels MJJ; Departments of Molecular Genetics, Molecular Cell Biology and Electron Microscopy, School of Nutrition and Translational Research in Metabolism (NUTRIM), University of Maastricht; Universiteitssingel 50, ER 6229 ER, Maastricht, The Netherlands.
  • Verheyen F; Departments of Molecular Genetics, Molecular Cell Biology and Electron Microscopy, School of Nutrition and Translational Research in Metabolism (NUTRIM), University of Maastricht; Universiteitssingel 50, ER 6229 ER, Maastricht, The Netherlands.
  • Lütjohann D; Institute of Clinical Chemistry and Clinical Pharmacology, University of Bonn; Sigmund-Freud-Str. 25, D-53127, Bonn, Germany.
  • Hofker MH; Department of Pathology and Medical Biology, Molecular Genetics, Medical Biology Section, University of Groningen, University Medical Center Groningen; Hanzeplein 1, 9713 GZ, Groningen, The Netherlands.
  • Binder CJ; Department of Laboratory Medicine, Medical University of Vienna; Spitalgasse 23, 1090, Vienna, Austria.
  • Shiri-Sverdlov R; Center for Molecular Medicine (CeMM), Austrian Academy of Sciences; Lazarettgasse 14, A-1090, Vienna, Austria.
Sci Rep ; 7(1): 12550, 2017 10 02.
Article em En | MEDLINE | ID: mdl-28970532
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Hepatopatia Gordurosa não Alcoólica / Inflamação / Lipoproteínas LDL / Macrófagos Idioma: En Ano de publicação: 2017 Tipo de documento: Article
Texto completo
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PubMed Links
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Hepatopatia Gordurosa não Alcoólica / Inflamação / Lipoproteínas LDL / Macrófagos Idioma: En Ano de publicação: 2017 Tipo de documento: Article