Attenuated phenotypes and analysis of a herpes simplex virus 1 strain with partial deletion of the UL7, UL41 and LAT genes.

Xu, Xingli; Guo, Yingqiu; Fan, Shengtao; Cui, Pingfang; Feng, Min; Wang, Lichun; Zhang, Ying; Liao, Yun; Zhang, Xiaolong; Li, Qihan

Xu, Xingli; Guo, Yingqiu; Fan, Shengtao; Cui, Pingfang; Feng, Min; Wang, Lichun; Zhang, Ying; Liao, Yun; Zhang, Xiaolong; Li, Qihan.

Afiliação

Xu X; Institute of Medical Biology, Chinese Academy of Medical Sciences and Peking Union Medical College, Yunnan Key Laboratory of Vaccine Research and Development of Severe Infectious Disease, Kunming, 650118, China.
Guo Y; Institute of Medical Biology, Chinese Academy of Medical Sciences and Peking Union Medical College, Yunnan Key Laboratory of Vaccine Research and Development of Severe Infectious Disease, Kunming, 650118, China.
Fan S; Institute of Medical Biology, Chinese Academy of Medical Sciences and Peking Union Medical College, Yunnan Key Laboratory of Vaccine Research and Development of Severe Infectious Disease, Kunming, 650118, China.
Cui P; Institute of Medical Biology, Chinese Academy of Medical Sciences and Peking Union Medical College, Yunnan Key Laboratory of Vaccine Research and Development of Severe Infectious Disease, Kunming, 650118, China.
Feng M; Institute of Medical Biology, Chinese Academy of Medical Sciences and Peking Union Medical College, Yunnan Key Laboratory of Vaccine Research and Development of Severe Infectious Disease, Kunming, 650118, China.
Wang L; Institute of Medical Biology, Chinese Academy of Medical Sciences and Peking Union Medical College, Yunnan Key Laboratory of Vaccine Research and Development of Severe Infectious Disease, Kunming, 650118, China.
Zhang Y; Institute of Medical Biology, Chinese Academy of Medical Sciences and Peking Union Medical College, Yunnan Key Laboratory of Vaccine Research and Development of Severe Infectious Disease, Kunming, 650118, China.
Liao Y; Institute of Medical Biology, Chinese Academy of Medical Sciences and Peking Union Medical College, Yunnan Key Laboratory of Vaccine Research and Development of Severe Infectious Disease, Kunming, 650118, China.
Zhang X; Institute of Medical Biology, Chinese Academy of Medical Sciences and Peking Union Medical College, Yunnan Key Laboratory of Vaccine Research and Development of Severe Infectious Disease, Kunming, 650118, China.
Li Q; Institute of Medical Biology, Chinese Academy of Medical Sciences and Peking Union Medical College, Yunnan Key Laboratory of Vaccine Research and Development of Severe Infectious Disease, Kunming, 650118, China. liqihan@imbcams.com.cn.

Virol Sin ; 32(5): 404-414, 2017 Oct.

Article em En | MEDLINE | ID: mdl-28971351

Assuntos

Proteínas Adaptadoras de Transdução de Sinal/genética; Proteínas Adaptadoras de Transdução de Sinal/metabolismo; Herpesvirus Humano 1/genética; Proteínas de Membrana/genética; Proteínas de Membrana/metabolismo; Proteínas da Matriz Viral/genética; Proteínas da Matriz Viral/metabolismo; Proteínas Virais/genética; Proteínas Virais/metabolismo; Animais; Linhagem Celular; Linhagem Celular Tumoral; Repetições Palindrômicas Curtas Agrupadas e Regularmente Espaçadas/genética; Células HEK293; Humanos; Imuno-Histoquímica; Hibridização In Situ; Íntrons/genética; Camundongos; Camundongos Endogâmicos BALB C; Mutação/genética; Tecido Nervoso/metabolismo; Fenótipo; Reação em Cadeia da Polimerase Via Transcriptase Reversa; Gânglio Trigeminal/metabolismo

Palavras-chave

LAT; UL41; UL7; herpes simplex virus 1 (HSV-1); mutant

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Proteínas Virais / Proteínas da Matriz Viral / Herpesvirus Humano 1 / Proteínas Adaptadoras de Transdução de Sinal / Proteínas de Membrana Idioma: En Ano de publicação: 2017 Tipo de documento: Article

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