Productive replication of avian influenza viruses in chicken endothelial cells is determined by hemagglutinin cleavability and is related to innate immune escape.

Lion, Adrien; Richard, Mathilde; Esnault, Evelyne; Kut, Emmanuel; Soubieux, Denis; Guillory, Vanaïque; Germond, Mélody; Blondeau, Caroline; Guabiraba, Rodrigo; Short, Kirsty R; Marc, Daniel; Quéré, Pascale; Trapp, Sascha

Lion, Adrien; Richard, Mathilde; Esnault, Evelyne; Kut, Emmanuel; Soubieux, Denis; Guillory, Vanaïque; Germond, Mélody; Blondeau, Caroline; Guabiraba, Rodrigo; Short, Kirsty R; Marc, Daniel; Quéré, Pascale; Trapp, Sascha.

Afiliação

Lion A; INRA ISP, Université François Rabelais de Tours, UMR 1282, Nouzilly, France.
Richard M; Erasmus Medical Center, Department of Viroscience, Rotterdam, The Netherlands.
Esnault E; INRA ISP, Université François Rabelais de Tours, UMR 1282, Nouzilly, France.
Kut E; INRA ISP, Université François Rabelais de Tours, UMR 1282, Nouzilly, France.
Soubieux D; INRA ISP, Université François Rabelais de Tours, UMR 1282, Nouzilly, France.
Guillory V; INRA ISP, Université François Rabelais de Tours, UMR 1282, Nouzilly, France.
Germond M; INRA ISP, Université François Rabelais de Tours, UMR 1282, Nouzilly, France.
Blondeau C; INRA ISP, Université François Rabelais de Tours, UMR 1282, Nouzilly, France.
Guabiraba R; INRA ISP, Université François Rabelais de Tours, UMR 1282, Nouzilly, France.
Short KR; Erasmus Medical Center, Department of Viroscience, Rotterdam, The Netherlands; University of Queensland, School of Biomedical Sciences, Brisbane, Australia.
Marc D; INRA ISP, Université François Rabelais de Tours, UMR 1282, Nouzilly, France.
Quéré P; INRA ISP, Université François Rabelais de Tours, UMR 1282, Nouzilly, France.
Trapp S; INRA ISP, Université François Rabelais de Tours, UMR 1282, Nouzilly, France. Electronic address: sascha.trapp@inra.fr.

Virology ; 513: 29-42, 2018 01 01.

Article em En | MEDLINE | ID: mdl-29031164

Assuntos

Células Endoteliais/virologia; Glicoproteínas de Hemaglutininação de Vírus da Influenza/metabolismo; Evasão da Resposta Imune; Imunidade Inata; Vírus da Influenza A/fisiologia; Internalização do Vírus; Replicação Viral; Animais; Galinhas; Células Endoteliais/imunologia; Vírus da Influenza A/imunologia; Proteólise

Palavras-chave

Avian influenza; Cell tropism; Chicken; Endothelial cells; Inflammation; Influenza A virus; Innate immunity; Pathogenesis; Poultry; Virus-host interactions

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Vírus da Influenza A / Replicação Viral / Glicoproteínas de Hemaglutininação de Vírus da Influenza / Células Endoteliais / Internalização do Vírus / Evasão da Resposta Imune / Imunidade Inata Idioma: En Ano de publicação: 2018 Tipo de documento: Article

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