Synthesis, pharmacological screening and computational analysis of some 2-(1H-Indol-3-yl)-N'-[(un)substituted phenylmethylidene] acetohydrazides and 2-(1H-Indol-3-yl)-N'-[(un)substituted benzoyl/2-thienylcarbonyl]acetohydrazides.

Rubab, Kaniz; Abbasi, Muhammad Athar; Rehman, Azizur; Siddiqui, Sabahat Zahra; Shah, Syed Adnan Ali; Ashraf, Muhammad; Ain, Quratul; Ahmad, Irshad; Lodhi, Muhammad Arif; Ghufran, Mehreen; Shahid, Muhammad; Fatima, Hina

Rubab, Kaniz; Abbasi, Muhammad Athar; Rehman, Azizur; Siddiqui, Sabahat Zahra; Shah, Syed Adnan Ali; Ashraf, Muhammad; Ain, Quratul; Ahmad, Irshad; Lodhi, Muhammad Arif; Ghufran, Mehreen; Shahid, Muhammad; Fatima, Hina.

Afiliação

Rubab K; Department of Chemistry, Government College University, Lahore, Pakistan.
Abbasi MA; Department of Chemistry, Government College University, Lahore, Pakistan.
Rehman A; Department of Chemistry, Government College University, Lahore, Pakistan.
Siddiqui SZ; Department of Chemistry, Government College University, Lahore, Pakistan.
Shah SAA; Faculty of Pharmacy, Universiti Teknologi MARA, Puncak Alam Campus, Bandar Puncak Alam, Selangor Darul Ehsan, Malaysia / Atta-ur-Rahman Institute for Natural Products Discovery (AuRIns), Level 9, FF3, Universiti Teknologi MARA, Puncak Alam Campus, 42300 Bandar Puncak Alam, Selangor Darul Ehsan, Mala
Ashraf M; Department of Chemistry, The Islamia University of Bahawalpur, Bahawalpur, Pakistan.
Ain Q; Department of Chemistry, The Islamia University of Bahawalpur, Bahawalpur, Pakistan.
Ahmad I; Department of Pharmacy; The Islamia University of Bahawalpur, Bahawalpur, Pakistan.
Lodhi MA; Department of Biochemistry, Abdul Wali Khan University, Mardan, Pakistan.
Shahid M; Department of Biochemistry, University of Agriculture, Faisalabad, Pakistan.
Fatima H; Department of Biochemistry, University of Agriculture, Faisalabad, Pakistan.

Pak J Pharm Sci ; 30(4): 1263-1274, 2017 Jul.

Article em En | MEDLINE | ID: mdl-29039324

Assuntos

Hidrazinas/síntese química; Hidrazinas/farmacologia; Animais; Antibacterianos/efeitos adversos; Antibacterianos/síntese química; Antibacterianos/farmacologia; Bovinos; Inibidores da Colinesterase/efeitos adversos; Inibidores da Colinesterase/síntese química; Inibidores da Colinesterase/farmacologia; Inibidores de Glicosídeo Hidrolases/efeitos adversos; Inibidores de Glicosídeo Hidrolases/síntese química; Inibidores de Glicosídeo Hidrolases/farmacologia; Hemolíticos/efeitos adversos; Hemolíticos/síntese química; Hemolíticos/farmacologia; Hidrazinas/efeitos adversos; Concentração Inibidora 50; Inibidores de Lipoxigenase/efeitos adversos; Inibidores de Lipoxigenase/síntese química; Inibidores de Lipoxigenase/farmacologia; Testes de Sensibilidade Microbiana; Simulação de Acoplamento Molecular; Relação Estrutura-Atividade

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