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Phosphorylation of eIF2α suppresses cisplatin-induced p53 activation and apoptosis by attenuating oxidative stress via ATF4-mediated HO-1 expression in human renal proximal tubular cells.
Ju, Sung-Min; Jo, Yong-Seok; Jeon, Yoo-Min; Pae, Hyun-Ock; Kang, Dae-Gill; Lee, Ho-Sub; Bae, Jun-Sang; Jeon, Byung-Hun.
Afiliação
  • Ju SM; Department of Pathology, College of Korean Medicine, Wonkwang University, Iksan, Jeonbuk 54538, Republic of Korea.
  • Jo YS; Department of Pathology, College of Korean Medicine, Wonkwang University, Iksan, Jeonbuk 54538, Republic of Korea.
  • Jeon YM; Department of Pathology, College of Korean Medicine, Wonkwang University, Iksan, Jeonbuk 54538, Republic of Korea.
  • Pae HO; Department of Microbiology and Immunology, School of Medicine, Wonkwang University, Iksan, Jeonbuk 54538, Republic of Korea.
  • Kang DG; Hanbang Cardio-Renal Syndrome Research Center, Wonkwang University, Iksan, Jeonbuk 54538, Republic of Korea.
  • Lee HS; Hanbang Cardio-Renal Syndrome Research Center, Wonkwang University, Iksan, Jeonbuk 54538, Republic of Korea.
  • Bae JS; Department of Pathology, Chonbuk National University Medical School, Research Institute of Clinical Medicine and Institute for Medical Sciences, Jeonju, Jeonbuk 54907, Republic of Korea.
  • Jeon BH; Department of Pathology, College of Korean Medicine, Wonkwang University, Iksan, Jeonbuk 54538, Republic of Korea.
Int J Mol Med ; 40(6): 1957-1964, 2017 Dec.
Article em En | MEDLINE | ID: mdl-29039478
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Fator de Iniciação 2 em Eucariotos / Proteína Supressora de Tumor p53 / Cisplatino / EIF-2 Quinase / Heme Oxigenase-1 / Fator 4 Ativador da Transcrição / Antineoplásicos Idioma: En Ano de publicação: 2017 Tipo de documento: Article
Texto completo
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Fator de Iniciação 2 em Eucariotos / Proteína Supressora de Tumor p53 / Cisplatino / EIF-2 Quinase / Heme Oxigenase-1 / Fator 4 Ativador da Transcrição / Antineoplásicos Idioma: En Ano de publicação: 2017 Tipo de documento: Article