[The vessel and primary glaucoma].

ABSTRACT

Glaucoma, as the first leading cause of irreversible blindness in the world, is a chronic progressive optic neuropathy. The pathogenesis of glaucoma is still not fully understood till now. A lot of studies about vascular diameter, tortuosity, location, disc perfusion, vascular regulation and systemic vascular factors had been conducted to investigate the relationship between the vascular states and glaucoma since vascular hypothesis proposed. However, direct and convincing evidence for primary mechanisms of glaucoma is still lacking. The development of OCT, especially the Angio-OCT makes the real time visualization and measurement of ocular perfusion in vivo possible, gives some new evidences of vascular dysfunction of optic nerve head associated with glaucoma, which enhancing thinking of the pathogenesis of glaucoma. This review summarizes the literatures on vascular factors associated with glaucoma to provide the references for clinical researches. (Chin J Ophthalmol, 2017, 53791-796).