[Effect of total flavonoids in Scutellaria barbata in mediating autophagy in tumor cells via PI3K/AKT/mTOR pathway].

Chen, Ming; Wang, Ju-Tao; Wu, Zhen-Ni; Hu, Man-Yan; Gao, Hua-Wu

Chen, Ming; Wang, Ju-Tao; Wu, Zhen-Ni; Hu, Man-Yan; Gao, Hua-Wu.

Afiliação

Chen M; Department of Pharmacology, Anhui University of Traditional Chinese Medicine, Hefei 230038, China.
Wang JT; Department of Pharmacology, Anhui University of Traditional Chinese Medicine, Hefei 230038, China.
Wu ZN; Department of Pharmacology, Anhui University of Traditional Chinese Medicine, Hefei 230038, China.
Hu MY; Department of Pharmacology, Anhui University of Traditional Chinese Medicine, Hefei 230038, China.
Gao HW; Department of Pharmacology, Anhui University of Traditional Chinese Medicine, Hefei 230038, China.

Zhongguo Zhong Yao Za Zhi ; 42(7): 1358-1364, 2017 Apr.

Article em Zh | MEDLINE | ID: mdl-29052399

Assuntos

Autofagia/efeitos dos fármacos; Flavonoides/farmacologia; Neoplasias Experimentais/tratamento farmacológico; Scutellaria/química; Transdução de Sinais; Animais; Apoptose; Melanoma/tratamento farmacológico; Camundongos; Fosfatidilinositol 3-Quinases; Proteínas Proto-Oncogênicas c-akt; Serina-Treonina Quinases TOR

Palavras-chave

PI3K/AKT/mTOR pathway; apoptosis; autophagy; total flavonoids in Scutellaria barbata

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Autofagia / Flavonoides / Transdução de Sinais / Scutellaria / Neoplasias Experimentais Idioma: Zh Ano de publicação: 2017 Tipo de documento: Article

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