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Ocular tissue distribution and pharmacokinetic study of a small 13kDa domain antibody after intravitreal, subconjuctival and eye drop administration in rabbits.
Gough, Gerald; Szapacs, Matthew; Shah, Tejash; Clements, Peter; Struble, Craig; Wilson, Robert.
Afiliação
  • Gough G; GlaxoSmithKline, BioPharm Research and Development, Gunnels Wood Road, Stevenage, Hertfordshire, UK. Electronic address: gerald.w.gough@gsk.com.
  • Szapacs M; GlaxoSmithKline Research and Development, Drug Metabolism and Pharmacokinetics, 709 Swedeland Road, King of Prussia, PA 19406, USA.
  • Shah T; GlaxoSmithKline, BioPharm Research and Development, Gunnels Wood Road, Stevenage, Hertfordshire, UK.
  • Clements P; GlaxoSmithKline, Research and Development, Global Comparative & Translational Sciences, David Jack Centre for R&D, Park Road, Ware, Hertfordshire, UK.
  • Struble C; Covance Laboratories Inc, 3301 Kinsman Boulevard, Madison, WI 53704-2595, USA.
  • Wilson R; GlaxoSmithKline, BioPharm Research and Development, Gunnels Wood Road, Stevenage, Hertfordshire, UK.
Exp Eye Res ; 167: 14-17, 2018 02.
Article em En | MEDLINE | ID: mdl-29074387
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Receptores Tipo I de Fatores de Necrose Tumoral / Olho / Anticorpos de Domínio Único / Anticorpos Monoclonais Idioma: En Ano de publicação: 2018 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Receptores Tipo I de Fatores de Necrose Tumoral / Olho / Anticorpos de Domínio Único / Anticorpos Monoclonais Idioma: En Ano de publicação: 2018 Tipo de documento: Article