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Pharmacophore Hybridization To Discover Novel Topoisomerase II Poisons with Promising Antiproliferative Activity.
Ortega, Jose Antonio; Riccardi, Laura; Minniti, Elirosa; Borgogno, Marco; Arencibia, Jose M; Greco, Maria L; Minarini, Anna; Sissi, Claudia; De Vivo, Marco.
Afiliação
  • Ortega JA; Laboratory of Molecular Modeling and Drug Discovery, Istituto Italiano di Tecnologia , Via Morego 30, 16163 Genova, Italy.
  • Riccardi L; Laboratory of Molecular Modeling and Drug Discovery, Istituto Italiano di Tecnologia , Via Morego 30, 16163 Genova, Italy.
  • Minniti E; Laboratory of Molecular Modeling and Drug Discovery, Istituto Italiano di Tecnologia , Via Morego 30, 16163 Genova, Italy.
  • Borgogno M; Department of Pharmacy and Biotechnology, Alma Mater Studiorum-University of Bologna , Via Belmeloro 6, 40126 Bologna, Italy.
  • Arencibia JM; Laboratory of Molecular Modeling and Drug Discovery, Istituto Italiano di Tecnologia , Via Morego 30, 16163 Genova, Italy.
  • Greco ML; Laboratory of Molecular Modeling and Drug Discovery, Istituto Italiano di Tecnologia , Via Morego 30, 16163 Genova, Italy.
  • Minarini A; Department of Pharmaceutical and Pharmacological Sciences, University of Padova , Via Marzolo 5, 35131 Padova, Italy.
  • Sissi C; Department of Pharmacy and Biotechnology, Alma Mater Studiorum-University of Bologna , Via Belmeloro 6, 40126 Bologna, Italy.
  • De Vivo M; Department of Pharmaceutical and Pharmacological Sciences, University of Padova , Via Marzolo 5, 35131 Padova, Italy.
J Med Chem ; 61(3): 1375-1379, 2018 02 08.
Article em En | MEDLINE | ID: mdl-29077404
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Desenho de Fármacos / DNA Topoisomerases Tipo II / Inibidores da Topoisomerase II Idioma: En Ano de publicação: 2018 Tipo de documento: Article
Texto completo
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XML
PubMed Links
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Desenho de Fármacos / DNA Topoisomerases Tipo II / Inibidores da Topoisomerase II Idioma: En Ano de publicação: 2018 Tipo de documento: Article