[Quality evaluation of Gualou Guizhi decoction based on chemical compositions and biological effects].
Zhongguo Zhong Yao Za Zhi
; 42(10): 1877-1882, 2017 May.
Article
em Zh
| MEDLINE
| ID: mdl-29090546
ABSTRACT
The paper was aimed to establish a quality evaluation model for Gualou Guizhi decoction based on the chemical compositions and biological effects. Ultra high performance liquid chromatograph-mass spectrometer was used to analyze and determine 24 kinds of chemical compositions in Gualou Guizhi decoction, and then, biological activity effect was quantitatively assessed in a zebrafish neuronal injury model which was induced by mycophenolate mofetil (MMF). As a result, the established method for quality evaluation of Gualou Guizhi decoction based on the chemical compositions and biological effects is feasible, stable and reliable, which can provide reference for quality control of compound Chinese medicines.
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1
Base de dados:
MEDLINE
Assunto principal:
Controle de Qualidade
/
Medicamentos de Ervas Chinesas
Idioma:
Zh
Ano de publicação:
2017
Tipo de documento:
Article