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Availability and Patterns of Intravesical BCG Instillations.
Poletajew, S Awomir; Majek, Aleksandra; Magusiak, Piotr; Ledzikowska, Katarzyna; Dybowski, Bartosz; Radziszewski, Piotr.
Afiliação
  • Poletajew SA; Department of Urology, Medical University of Warsaw, Warsaw, Poland.. slawomir.poletajew@wum.edu.pl.
  • Majek A; Department of Urology, Medical University of Warsaw, Warsaw, Poland.
  • Magusiak P; Department of Urology, Medical University of Warsaw, Warsaw, Poland.
  • Ledzikowska K; Department of Urology, Medical University of Warsaw, Warsaw, Poland.
  • Dybowski B; Department of Urology, Medical University of Warsaw, Warsaw, Poland.
  • Radziszewski P; Department of Urology, Medical University of Warsaw, Warsaw, Poland.
Urol J ; 14(6): 5068-5070, 2017 Nov 04.
Article em En | MEDLINE | ID: mdl-29101762
ABSTRACT

PURPOSE:

Intravesical BCG instillations improve recurrence free survival in patients with non-muscle-invasive bladder cancer (NMIBC).

METHODS:

This is a national survey study, covering 223 urological centres, aimed at reliable identification of BCG availability and implemented treatment patterns.

RESULTS:

Response rate was 93.7%. BCG was used in 56.5% of urological departments. Another 22.7% referred patients to other hospitals for instillations, while 20.8% did not recommend BCG at all. The most common indications for BCG instillations were as follows T1 tumours (88.5%), carcinoma in situ (83.6%) and high grade tumours (73.8%). Maintenance therapy was routinely abandoned in 16.4% of centres or was scheduled for <1 year, 1 year, 3 years and 1-3 years in 6.6%, 19.7%, 21.3% and 31.2% of centres, respectively. Continuation of BCGdespite treatment failure in carcinoma in situ cases was considered in 21.3% of departments.

CONCLUSION:

Our findings indicate that BCG is underused, while patterns of maintenance and follow-up are suboptimal.
Assuntos

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias da Bexiga Urinária / Vacina BCG / Carcinoma in Situ / Adjuvantes Imunológicos Idioma: En Ano de publicação: 2017 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias da Bexiga Urinária / Vacina BCG / Carcinoma in Situ / Adjuvantes Imunológicos Idioma: En Ano de publicação: 2017 Tipo de documento: Article