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HIF and HOIL-1L-mediated PKCζ degradation stabilizes plasma membrane Na,K-ATPase to protect against hypoxia-induced lung injury.
Magnani, Natalia D; Dada, Laura A; Queisser, Markus A; Brazee, Patricia L; Welch, Lynn C; Anekalla, Kishore R; Zhou, Guofei; Vagin, Olga; Misharin, Alexander V; Budinger, G R Scott; Iwai, Kazuhiro; Ciechanover, Aaron J; Sznajder, Jacob I.
Afiliação
  • Magnani ND; Pulmonary and Critical Care Division, Northwestern Feinberg School of Medicine, Chicago, IL, 60611.
  • Dada LA; Pulmonary and Critical Care Division, Northwestern Feinberg School of Medicine, Chicago, IL, 60611.
  • Queisser MA; Pulmonary and Critical Care Division, Northwestern Feinberg School of Medicine, Chicago, IL, 60611.
  • Brazee PL; Pulmonary and Critical Care Division, Northwestern Feinberg School of Medicine, Chicago, IL, 60611.
  • Welch LC; Pulmonary and Critical Care Division, Northwestern Feinberg School of Medicine, Chicago, IL, 60611.
  • Anekalla KR; Pulmonary and Critical Care Division, Northwestern Feinberg School of Medicine, Chicago, IL, 60611.
  • Zhou G; Pulmonary and Critical Care Division, Northwestern Feinberg School of Medicine, Chicago, IL, 60611.
  • Vagin O; Department of Physiology, David Geffen School of Medicine, Los Angeles, CA 10833.
  • Misharin AV; University of California at Los Angeles and Veterans Administration Greater Los Angeles Healthcare System, Los Angeles, CA 90095.
  • Budinger GRS; Pulmonary and Critical Care Division, Northwestern Feinberg School of Medicine, Chicago, IL, 60611.
  • Iwai K; Pulmonary and Critical Care Division, Northwestern Feinberg School of Medicine, Chicago, IL, 60611.
  • Ciechanover AJ; Department of Molecular and Cellular Physiology, Graduate School of Medicine, Kyoto University, Kyoto, Japan, 606-8501.
  • Sznajder JI; Rappaport Faculty of Medicine and Research Institute, Technion Integrated Cancer Center, Haifa, Israel 3109601 aaroncie@technion.ac.il j-sznajder@northwestern.edu.
Proc Natl Acad Sci U S A ; 114(47): E10178-E10186, 2017 11 21.
Article em En | MEDLINE | ID: mdl-29109255
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Proteína Quinase C / Proteínas de Transporte / ATPase Trocadora de Sódio-Potássio / Subunidade alfa do Fator 1 Induzível por Hipóxia / Lesão Pulmonar / Hipóxia Idioma: En Ano de publicação: 2017 Tipo de documento: Article
Texto completo
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Proteína Quinase C / Proteínas de Transporte / ATPase Trocadora de Sódio-Potássio / Subunidade alfa do Fator 1 Induzível por Hipóxia / Lesão Pulmonar / Hipóxia Idioma: En Ano de publicação: 2017 Tipo de documento: Article