Repeated inhalation of sevoflurane inhibits the information transmission of Purkinje cells and delays motor development via the GABAA receptor Îµ subunit in neonatal mice.

Fang, Hong; Wang, Ze-Hua; Bu, Ying-Jiang; Yuan, Zhi-Jun; Wang, Guo-Qiang; Guo, Yan; Cheng, Xiao-Yun; Qiu, Wen-Jie

Fang, Hong; Wang, Ze-Hua; Bu, Ying-Jiang; Yuan, Zhi-Jun; Wang, Guo-Qiang; Guo, Yan; Cheng, Xiao-Yun; Qiu, Wen-Jie.

Afiliação

Fang H; Department of Anesthesiology, The Affiliated Heji Hospital of Changzhi Medical College, Changzhi, Shanxi 046011, P.R. China.
Wang ZH; Department of Anesthesiology, The Affiliated Heji Hospital of Changzhi Medical College, Changzhi, Shanxi 046011, P.R. China.
Bu YJ; Department of Anesthesiology, The Affiliated Heji Hospital of Changzhi Medical College, Changzhi, Shanxi 046011, P.R. China.
Yuan ZJ; Department of Anesthesiology, The Affiliated Heji Hospital of Changzhi Medical College, Changzhi, Shanxi 046011, P.R. China.
Wang GQ; Department of Anesthesiology, The Affiliated Heji Hospital of Changzhi Medical College, Changzhi, Shanxi 046011, P.R. China.
Guo Y; Department of Anesthesiology, The Affiliated Heji Hospital of Changzhi Medical College, Changzhi, Shanxi 046011, P.R. China.
Cheng XY; Department of Anesthesiology, The Suburban People's Hospital, Changzhi, Shanxi 046011, P.R. China.
Qiu WJ; Department of Anesthesiology, The Suburban People's Hospital, Changzhi, Shanxi 046011, P.R. China.

Mol Med Rep ; 17(1): 1083-1092, 2018 Jan.

Article em En | MEDLINE | ID: mdl-29115488

Assuntos

Anestésicos Inalatórios/administração & dosagem; Éteres Metílicos/administração & dosagem; Células de Purkinje/efeitos dos fármacos; Células de Purkinje/fisiologia; Receptores de GABA-A/metabolismo; Transmissão Sináptica/efeitos dos fármacos; Animais; Animais Recém-Nascidos; Comportamento Animal; Córtex Cerebelar/efeitos dos fármacos; Córtex Cerebelar/fisiologia; Feminino; Locomoção/efeitos dos fármacos; Camundongos; Camundongos Knockout; Receptores de GABA-A/genética; Sevoflurano

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Células de Purkinje / Receptores de GABA-A / Transmissão Sináptica / Anestésicos Inalatórios / Éteres Metílicos Idioma: En Ano de publicação: 2018 Tipo de documento: Article

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