The Encyclopedia of DNA elements (ENCODE): data portal update.
Nucleic Acids Res
; 46(D1): D794-D801, 2018 01 04.
Article
em En
| MEDLINE
| ID: mdl-29126249
ABSTRACT
The Encyclopedia of DNA Elements (ENCODE) Data Coordinating Center has developed the ENCODE Portal database and website as the source for the data and metadata generated by the ENCODE Consortium. Two principles have motivated the design. First, experimental protocols, analytical procedures and the data themselves should be made publicly accessible through a coherent, web-based search and download interface. Second, the same interface should serve carefully curated metadata that record the provenance of the data and justify its interpretation in biological terms. Since its initial release in 2013 and in response to recommendations from consortium members and the wider community of scientists who use the Portal to access ENCODE data, the Portal has been regularly updated to better reflect these design principles. Here we report on these updates, including results from new experiments, uniformly-processed data from other projects, new visualization tools and more comprehensive metadata to describe experiments and analyses. Additionally, the Portal is now home to meta(data) from related projects including Genomics of Gene Regulation, Roadmap Epigenome Project, Model organism ENCODE (modENCODE) and modERN. The Portal now makes available over 13000 datasets and their accompanying metadata and can be accessed at https//www.encodeproject.org/.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
DNA
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Genômica
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Bases de Dados Genéticas
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Componentes do Gene
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Sequenciamento de Nucleotídeos em Larga Escala
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Metadados
Idioma:
En
Ano de publicação:
2018
Tipo de documento:
Article