Chemo-biologic combinatorial drug delivery using folate receptor-targeted dendrimer nanoparticles for lung cancer treatment.

Amreddy, Narsireddy; Babu, Anish; Panneerselvam, Janani; Srivastava, Akhil; Muralidharan, Ranganayaki; Chen, Allshine; Zhao, Yan D; Munshi, Anupama; Ramesh, Rajagopal

Amreddy, Narsireddy; Babu, Anish; Panneerselvam, Janani; Srivastava, Akhil; Muralidharan, Ranganayaki; Chen, Allshine; Zhao, Yan D; Munshi, Anupama; Ramesh, Rajagopal.

Afiliação

Amreddy N; Department of Pathology, University of Oklahoma Health Sciences Center, Oklahoma City, OK, USA; Stephenson Cancer Center, University of Oklahoma Health Sciences Center, Oklahoma City, OK, USA.
Babu A; Department of Pathology, University of Oklahoma Health Sciences Center, Oklahoma City, OK, USA; Stephenson Cancer Center, University of Oklahoma Health Sciences Center, Oklahoma City, OK, USA.
Panneerselvam J; Department of Pathology, University of Oklahoma Health Sciences Center, Oklahoma City, OK, USA; Stephenson Cancer Center, University of Oklahoma Health Sciences Center, Oklahoma City, OK, USA.
Srivastava A; Department of Pathology, University of Oklahoma Health Sciences Center, Oklahoma City, OK, USA; Stephenson Cancer Center, University of Oklahoma Health Sciences Center, Oklahoma City, OK, USA.
Muralidharan R; Department of Pathology, University of Oklahoma Health Sciences Center, Oklahoma City, OK, USA; Stephenson Cancer Center, University of Oklahoma Health Sciences Center, Oklahoma City, OK, USA.
Chen A; Department of Biostatistics and Epidemiology, University of Oklahoma Health Sciences Center, Oklahoma City, OK, USA.
Zhao YD; Department of Biostatistics and Epidemiology, University of Oklahoma Health Sciences Center, Oklahoma City, OK, USA; Stephenson Cancer Center, University of Oklahoma Health Sciences Center, Oklahoma City, OK, USA.
Munshi A; Department of Radiation Oncology, University of Oklahoma Health Sciences Center, Oklahoma City, OK, USA; Stephenson Cancer Center, University of Oklahoma Health Sciences Center, Oklahoma City, OK, USA.
Ramesh R; Department of Pathology, University of Oklahoma Health Sciences Center, Oklahoma City, OK, USA; Stephenson Cancer Center, University of Oklahoma Health Sciences Center, Oklahoma City, OK, USA; Graduate Program in Biomedical Sciences, University of Oklahoma Health Sciences Center, Oklahoma City, OK,

Nanomedicine ; 14(2): 373-384, 2018 02.

Article em En | MEDLINE | ID: mdl-29155362

Assuntos

Carcinoma Pulmonar de Células não Pequenas/terapia; Cisplatino/farmacologia; Dendrímeros/química; Sistemas de Liberação de Medicamentos; Proteína Semelhante a ELAV 1/antagonistas & inibidores; Receptor 1 de Folato/metabolismo; Nanopartículas/administração & dosagem; Antineoplásicos/farmacologia; Apoptose/efeitos dos fármacos; Carcinoma Pulmonar de Células não Pequenas/genética; Carcinoma Pulmonar de Células não Pequenas/patologia; Proliferação de Células/efeitos dos fármacos; Terapia Combinada; Proteína Semelhante a ELAV 1/genética; Humanos; Neoplasias Pulmonares/genética; Neoplasias Pulmonares/patologia; Neoplasias Pulmonares/terapia; Nanopartículas/química; RNA Interferente Pequeno/genética; Células Tumorais Cultivadas

Palavras-chave

CDDP; Dendrimer; FRA; HuR siRNA; Lung cancer

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Cisplatino / Sistemas de Liberação de Medicamentos / Carcinoma Pulmonar de Células não Pequenas / Dendrímeros / Nanopartículas / Receptor 1 de Folato / Proteína Semelhante a ELAV 1 Idioma: En Ano de publicação: 2018 Tipo de documento: Article

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