The hidden pathogenic potential of environmental fungi.
Future Microbiol
; 12: 1533-1540, 2017 12.
Article
em En
| MEDLINE
| ID: mdl-29168657
ABSTRACT
Invasive fungal infections are a growing threat to immunocompromised patients, highlighting the importance of monitoring fungal pathogens. Global warming (including climatic oscillations) may select for environmental species that have acquired thermotolerance, a key step toward pathogenesis to humans. Also, important virulence factors have developed in environmental fungi, because they are essential for yeast survival in the environment. Thus, fungi traditionally regarded as nonpathogenic to humans have virulence factors similar to those of their pathogenic relatives. Here, we highlight the emergence of saprophytic environmental fungi - including species of Cryptococcus, Aspergillus, Penicillium, Candida and Scedosporium - as new human pathogens. Emerging pathogens are, in some cases, resistant to the available antifungals, potentiating the threat of novel fungal diseases.
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Texto completo:
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Base de dados:
MEDLINE
Assunto principal:
Microbiologia Ambiental
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Infecções Fúngicas Invasivas
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Fungos
Idioma:
En
Ano de publicação:
2017
Tipo de documento:
Article