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Oxygen gradients can determine epigenetic asymmetry and cellular differentiation via differential regulation of Tet activity in embryonic stem cells.
Burr, Simon; Caldwell, Anna; Chong, Mei; Beretta, Matteo; Metcalf, Stephen; Hancock, Matthew; Arno, Matthew; Balu, Sucharitha; Kropf, Valeria Leon; Mistry, Rajesh K; Shah, Ajay M; Mann, Giovanni E; Brewer, Alison C.
Afiliação
  • Burr S; British Heart Foundation Centre of Research Excellence, Department of Cardiology, King's College London, London SE5 9NU, UK.
  • Caldwell A; King's Centre of Excellence for Mass Spectrometry, King's College London, London SE1 9NH, UK.
  • Chong M; British Heart Foundation Centre of Research Excellence, Department of Cardiology, King's College London, London SE5 9NU, UK.
  • Beretta M; British Heart Foundation Centre of Research Excellence, Department of Cardiology, King's College London, London SE5 9NU, UK.
  • Metcalf S; British Heart Foundation Centre of Research Excellence, Department of Cardiology, King's College London, London SE5 9NU, UK.
  • Hancock M; British Heart Foundation Centre of Research Excellence, Department of Cardiology, King's College London, London SE5 9NU, UK.
  • Arno M; King's Genomic Centre, King's College London, London SE1 9NH, UK.
  • Balu S; King's Genomic Centre, King's College London, London SE1 9NH, UK.
  • Kropf VL; British Heart Foundation Centre of Research Excellence, Department of Cardiology, King's College London, London SE5 9NU, UK.
  • Mistry RK; British Heart Foundation Centre of Research Excellence, Department of Cardiology, King's College London, London SE5 9NU, UK.
  • Shah AM; British Heart Foundation Centre of Research Excellence, Department of Cardiology, King's College London, London SE5 9NU, UK.
  • Mann GE; British Heart Foundation Centre of Research Excellence, Department of Cardiology, King's College London, London SE5 9NU, UK.
  • Brewer AC; British Heart Foundation Centre of Research Excellence, Department of Cardiology, King's College London, London SE5 9NU, UK.
Nucleic Acids Res ; 46(3): 1210-1226, 2018 02 16.
Article em En | MEDLINE | ID: mdl-29186571
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Oxigênio / Proteínas Proto-Oncogênicas / Regulação da Expressão Gênica no Desenvolvimento / Epigênese Genética / Dioxigenases / Células-Tronco Embrionárias Murinas / Oxigenases de Função Mista Idioma: En Ano de publicação: 2018 Tipo de documento: Article
Texto completo
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Oxigênio / Proteínas Proto-Oncogênicas / Regulação da Expressão Gênica no Desenvolvimento / Epigênese Genética / Dioxigenases / Células-Tronco Embrionárias Murinas / Oxigenases de Função Mista Idioma: En Ano de publicação: 2018 Tipo de documento: Article